Rbmx2 RNA binding motif protein, X-linked 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rbmx2provided by MGI
Official Full Name: RNA binding motif protein, X-linked 2provided by MGI
Primary source: MGI:MGI:1919414
See related: Ensembl:ENSMUSG00000031107 AllianceGenome:MGI:1919414
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: CGI-79; 2700089A17Rik; 2810411A03Rik
Summary: Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and U2-type precatalytic spliceosome. Orthologous to human RBMX2 (RNA binding motif protein X-linked 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E11.5 (RPKM 8.2), liver E14 (RPKM 7.3) and 19 other tissues See more
Orthologs: human all
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Genomic context

Location:: X A5; X 25.69 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (47783881..47799596)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (48695004..48710719)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:234542

Rbmx2 (e-PCR), detects polymorphism
- UniSTS:479029

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA splicing, via spliceosome	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of U2 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of U2-type precatalytic spliceosome	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in nuclear membrane	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of precatalytic spliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: RNA-binding motif protein, X-linked 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_173376.3 → NP_775552.1 RNA-binding motif protein, X-linked 2

See identical proteins and their annotated locations for NP_775552.1

Status: PROVISIONAL

Source sequence(s)

AL672042

Consensus CDS

CCDS30114.1

UniProtKB/Swiss-Prot

A2AF74, Q3TI42, Q8R0F5

Related

ENSMUSP00000033433.3, ENSMUST00000033433.3

Conserved Domains (2) summary

COG0724
Location:38 → 110

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12411
Location:27 → 115

RRM_ist3_like; RNA recognition motif in ist3 family