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OR9Q1 olfactory receptor family 9 subfamily Q member 1 [ Homo sapiens (human) ]

Gene ID: 219956, updated on 5-Mar-2024

Summary

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Official Symbol
OR9Q1provided by HGNC
Official Full Name
olfactory receptor family 9 subfamily Q member 1provided by HGNC
Primary source
HGNC:HGNC:14724
See related
Ensembl:ENSG00000186509 AllianceGenome:HGNC:14724
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
all
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Genomic context

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See OR9Q1 in Genome Data Viewer
Location:
11q12.1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (58023881..58181616)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (57974227..58131037)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (57791353..57949088)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily BD member 1 pseudogene Neighboring gene Sharpr-MPRA regulatory region 10633 Neighboring gene uncharacterized LOC107984331 Neighboring gene CYCS pseudogene 26 Neighboring gene RNA, U6 small nuclear 899, pseudogene Neighboring gene uncharacterized LOC124902674 Neighboring gene olfactory receptor family 6 subfamily Q member 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:57825504-57826184 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:57826185-57826864 Neighboring gene vomeronasal 2 receptor 9, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:57834537-57835036 Neighboring gene tRNA methyltransferase 11 homolog (S. cerevisiae) pseudogene Neighboring gene olfactory receptor family 9 subfamily L member 1 pseudogene Neighboring gene olfactory receptor family 9 subfamily I member 3 pseudogene Neighboring gene olfactory receptor family 9 subfamily I member 1 Neighboring gene olfactory receptor family 9 subfamily I member 2 pseudogene Neighboring gene olfactory receptor family 5 subfamily BL member 1 pseudogene Neighboring gene olfactory receptor family 9 subfamily Q member 2 Neighboring gene olfactory receptor family 1 subfamily S member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. DEFOG: a practical scheme for deciphering families of genes. Fuchs T, et al. Genomics, 2002 Sep. PMID 12213199
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Homology

Clone Names

  • MGC131737

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
olfactory receptor 9Q1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005212.4 → NP_001005212.1  olfactory receptor 9Q1

    See identical proteins and their annotated locations for NP_001005212.1

    Status: VALIDATED

    Source sequence(s)
    AP003484, AP004247
    Consensus CDS
    CCDS31543.1
    UniProtKB/Swiss-Prot
    Q2TAN3, Q8NGQ5, Q96RA7
    UniProtKB/TrEMBL
    A0A126GWR3
    Related
    ENSP00000334934.3, ENST00000335397.3
    Conserved Domains (1) summary
    cd15230
    Location:34 → 293
    7tmA_OR5-like; olfactory receptor family 5 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    58023881..58181616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    57974227..58131037
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8NGQ5.1 GenPept UniProtKB/Swiss-Prot:Q8NGQ5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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