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Rrp36 ribosomal RNA processing 36 [ Mus musculus (house mouse) ]

Gene ID: 224823, updated on 5-Mar-2024

Summary

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Official Symbol
Rrp36provided by MGI
Official Full Name
ribosomal RNA processing 36provided by MGI
Primary source
MGI:MGI:2385053
See related
Ensembl:ENSMUSG00000023971 AllianceGenome:MGI:2385053
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in nucleoplasm. Predicted to be part of 90S preribosome. Predicted to be active in nucleolus. Orthologous to human RRP36 (ribosomal RNA processing 36). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 14.7), ovary adult (RPKM 13.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Rrp36 in Genome Data Viewer
Location:
17 C; 17 22.9 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (46977249..46985252, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46666323..46674326, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene kinesin light chain 4 Neighboring gene STARR-positive B cell enhancer ABC_E7536 Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene cullin 7 Neighboring gene STARR-seq mESC enhancer starr_42676 Neighboring gene kelch domain containing 3 Neighboring gene STARR-positive B cell enhancer mm9_chr17:46817738-46818039 Neighboring gene male enhanced antigen 1 Neighboring gene protein phosphatase 2, regulatory subunit B', delta Neighboring gene STARR-positive B cell enhancer ABC_E7538

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Evolutionarily conserved function of RRP36 in early cleavages of the pre-rRNA and production of the 40S ribosomal subunit. Gérus M, et al. Mol Cell Biol, 2010 Mar. PMID 20038530, Free PMC Article
  2. A molecular profile of a hematopoietic stem cell niche. Hackney JA, et al. Proc Natl Acad Sci U S A, 2002 Oct 1. PMID 12226475, Free PMC Article
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC19067

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of 90S preribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal RNA processing protein 36 homolog
Names
RNA processing factor
ribosomal RNA processing 36 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368622.1 → NP_001355551.1  ribosomal RNA processing protein 36 homolog isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT030702
    UniProtKB/TrEMBL
    A0A0R4J045
    Conserved Domains (1) summary
    pfam06102
    Location:41 → 195
    RRP36; rRNA biogenesis protein RRP36

  2. NM_144857.2 → NP_659106.2  ribosomal RNA processing protein 36 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    BE647409, BQ833497, CT030702
    Consensus CDS
    CCDS37639.2
    UniProtKB/TrEMBL
    A0A0R4J045, A0A3B2WB30
    Related
    ENSMUSP00000156646.2, ENSMUST00000233136.2
    Conserved Domains (1) summary
    pfam06102
    Location:76 → 230
    RRP36; rRNA biogenesis protein RRP36

RNA

  1. NR_160853.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    BE647409, BQ833497, CT030702

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    46977249..46985252 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UFY0.1 GenPept UniProtKB/Swiss-Prot:Q3UFY0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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