Lancl3 LanC lantibiotic synthetase component C-like 3 (bacterial) [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Lancl3provided by MGI
Official Full Name: LanC lantibiotic synthetase component C-like 3 (bacterial)provided by MGI
Primary source: MGI:MGI:2443335
See related: Ensembl:ENSMUSG00000047344 AllianceGenome:MGI:2443335
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 6030463G20Rik
Summary: Predicted to be involved in carbohydrate metabolic process. Predicted to be active in plasma membrane. Orthologous to human LANCL3 (LanC like 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in cerebellum adult (RPKM 1.8), adrenal adult (RPKM 1.8) and 23 other tissues See more
Orthologs: human all
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Genomic context

Location:: X A1.1; X 4.18 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (9066212..9134324)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (9199973..9268085)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Very similar concentrations of lanthionine ketimine (0.5-2.5 nmol/g tissue) were found in LanCL1 knock-out, LanCL1/LanCL2/LanCL3 triple-knock-out and wild type (WT) mouse brains, suggesting that LanCL proteins are not involved in lanthionine biosynthesis.
Title: LanCL proteins are not Involved in Lanthionine Synthesis in Mammals.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3) 1 citation

General gene information

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Markers

px-70c3 (e-PCR)
- UniSTS:258152

px-57d7 (e-PCR)
- UniSTS:257954

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in peptide modification	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: lanC-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.