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Tmem37 transmembrane protein 37 [ Rattus norvegicus (Norway rat) ]

Gene ID: 245953, updated on 13-Apr-2024

Summary

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Official Symbol
Tmem37provided by RGD
Official Full Name
transmembrane protein 37provided by RGD
Primary source
RGD:628689
See related
Ensembl:ENSRNOG00000047714 AllianceGenome:RGD:628689
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Pr; Pr1
Summary
Predicted to enable calcium channel activity and voltage-gated ion channel activity. Predicted to be involved in calcium ion transmembrane transport and regulation of ion transmembrane transport. Predicted to be integral component of membrane. Orthologous to human TMEM37 (transmembrane protein 37). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 207.1), Liver (RPKM 173.3) and 6 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tmem37 in Genome Data Viewer
Location:
13q11
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (33737096..33743602, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (31184322..31191477, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (36094665..36101443, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 221 Neighboring gene uncharacterized LOC134481481 Neighboring gene secretin receptor Neighboring gene similar to chromosome 2 open reading frame 76 Neighboring gene diazepam binding inhibitor Neighboring gene STEAP3 metalloreductase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Calcium channel gamma subunits provide insights into the evolution of this gene family. Chu PJ, et al. Gene, 2001 Dec 12. PMID 11738816

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables calcium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables voltage-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of monoatomic ion channel complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
voltage-dependent calcium channel gamma-like subunit
Names
neuronal voltage-gated calcium channel gamma-like subunit
protein distantly related to to the gamma subunit family
voltage-dependent calcium channel gamma subunit-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139095.2 → NP_620795.2  voltage-dependent calcium channel gamma-like subunit

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    33737096..33743602 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008769424.4 → XP_008767646.1  voltage-dependent calcium channel gamma-like subunit isoform X1

    UniProtKB/TrEMBL
    A6K7Y6, M0RCX9
    Related
    ENSRNOP00000067466.2
    Conserved Domains (1) summary
    pfam15108
    Location:19 → 199
    TMEM37; Voltage-dependent calcium channel gamma-like subunit protein family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VHW1.1 GenPept UniProtKB/Swiss-Prot:Q8VHW1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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