U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GAGE5 G antigen 5 [ Homo sapiens (human) ]

Gene ID: 2577, updated on 10-Oct-2023

Summary

Official Symbol
GAGE5provided by HGNC
Official Full Name
G antigen 5provided by HGNC
Primary source
HGNC:HGNC:4102
See related
MIM:300598
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT4.5
Summary
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
Annotation information
Annotation category: not annotated on reference assembly
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
Xp11.4-p11.2
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (48810109..48817380)

Chromosome X - NC_060947.1Genomic Context describing neighboring genes Neighboring gene G antigen 7-like Neighboring gene G antigen 7-like Neighboring gene G antigen 5 Neighboring gene G antigen 7-like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_060947.1 Chromosome X Alternate T2T-CHM13v2.0

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
G antigen 5
Names
GAGE-5
cancer/testis antigen 4.5
cancer/testis antigen family 4, member 5

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001475.1NP_001466.1  G antigen 5

    See identical proteins and their annotated locations for NP_001466.1

    Status: REVIEWED

    Source sequence(s)
    U19146
    UniProtKB/Swiss-Prot
    Q13069, Q6FG72
    UniProtKB/TrEMBL
    B7ZVY3
    Conserved Domains (1) summary
    pfam05831
    Location:1111
    GAGE; GAGE protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    48810109..48817380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)