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PF3D7_0815900 dihydrolipoyl dehydrogenase, apicoplast [ Plasmodium falciparum 3D7 ]

Gene ID: 2655265, updated on 16-Oct-2023

Summary

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Gene symbol
PF3D7_0815900
Gene description
dihydrolipoyl dehydrogenase, apicoplast
Locus tag
PF3D7_0815900
Gene type
protein coding
RNA name
dihydrolipoyl dehydrogenase, apicoplast
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 8
Exon count:
1
Sequence:
Chromosome: 8; NC_004329.3 (743505..745505)

Chromosome 8 - NC_004329.3Genomic Context describing neighboring genes Neighboring gene ubiquitin Neighboring gene vacuolar protein sorting-associated protein 9, putative Neighboring gene ribosome assembly protein RRB1, putative Neighboring gene phosphopantothenoylcysteine decarboxylase, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004329.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Biochemical and structural characterization of the apicoplast dihydrolipoamide dehydrogenase of Plasmodium falciparum. Laine LM, et al. Biosci Rep, 2015 Jan 14. PMID 25387830, Free PMC Article
  2. The human malaria parasite Plasmodium falciparum possesses two distinct dihydrolipoamide dehydrogenases. McMillan PJ, et al. Mol Microbiol, 2005 Jan. PMID 15612914
  3. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables dihydrolipoyl dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within acetyl-CoA biosynthetic process from pyruvate IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in apicoplast HDA PubMed 
located_in apicoplast IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
dihydrolipoyl dehydrogenase, apicoplast
XP_001349365.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004329.3 Reference assembly

    Range
    743505..745505
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001349329.1 → XP_001349365.1  dihydrolipoyl dehydrogenase, apicoplast [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001349365.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024VL44, A0A024W9B6, A0A024WRY7, A0A0L1I6T7, A0A0L7M701, Q8IAZ6, W4IHW3, W7FGR5, W7G042, W7JE02, W7JVD0
    Conserved Domains (1) summary
    PTZ00153
    Location:11 → 666
    PTZ00153; lipoamide dehydrogenase; Provisional
Nucleotide Protein
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