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Slc35e4 solute carrier family 35, member E4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 266687, updated on 11-Apr-2024

Summary

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Official Symbol
Slc35e4provided by RGD
Official Full Name
solute carrier family 35, member E4provided by RGD
Primary source
RGD:708484
See related
Ensembl:ENSRNOG00000004168 AllianceGenome:RGD:708484
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable antiporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Orthologous to human SLC35E4 (solute carrier family 35 member E4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 103.6), Brain (RPKM 81.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
14q21
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (83026914..83033778, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (78803320..78810186, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (84163971..84170835, complement)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene transcription initiation factor IIA subunit 2-like Neighboring gene similar to human chromosome 5 open reading frame 52 Neighboring gene dual specificity phosphatase 18 Neighboring gene transcobalamin 2 Neighboring gene pescadillo ribosomal biogenesis factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC93128

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
solute carrier family 35 member E4
Names
putative phosphate-phosphoenolpyruvate translocator

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153316.2 → NP_695228.2  solute carrier family 35 member E4

    See identical proteins and their annotated locations for NP_695228.2

    Status: PROVISIONAL

    Source sequence(s)
    BC085693
    UniProtKB/Swiss-Prot
    Q5RKL7
    Related
    ENSRNOP00000005646.3, ENSRNOT00000005646.5
    Conserved Domains (3) summary
    pfam00892
    Location:188 → 324
    EamA; EamA-like transporter family
    pfam03151
    Location:54 → 325
    TPT; Triose-phosphate Transporter family
    cl23754
    Location:53 → 178
    EamA; EamA-like transporter family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    83026914..83033778 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039091642.2 → XP_038947570.1  solute carrier family 35 member E4 isoform X1

    Conserved Domains (1) summary
    cl26744
    Location:54 → 182
    TPT; Triose-phosphate Transporter family

  2. XM_039091643.2 → XP_038947571.1  solute carrier family 35 member E4 isoform X2

    Conserved Domains (1) summary
    cl26744
    Location:72 → 188
    TPT; Triose-phosphate Transporter family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RKL7.1 GenPept UniProtKB/Swiss-Prot:Q5RKL7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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