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Zfp512b zinc finger protein 512B [ Mus musculus (house mouse) ]

Gene ID: 269401, updated on 30-Apr-2024

Summary

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Official Symbol
Zfp512bprovided by MGI
Official Full Name
zinc finger protein 512Bprovided by MGI
Primary source
MGI:MGI:2685478
See related
Ensembl:ENSMUSG00000000823 AllianceGenome:MGI:2685478
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm632; Znf512b
Summary
Predicted to be located in nucleoplasm. Is expressed in lung. Orthologous to human ZNF512B (zinc finger protein 512B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 26.1), testis adult (RPKM 23.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 H4; 2 103.67 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (181223925..181234572, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181582103..181592972, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C5 Neighboring gene STARR-positive B cell enhancer ABC_E3426 Neighboring gene uridine-cytidine kinase 1-like 1 Neighboring gene uridine-cytidine kinase 1-like 1, opposite strand Neighboring gene microRNA 7006 Neighboring gene STARR-positive B cell enhancer mm9_chr2:181335875-181336176 Neighboring gene sterile alpha motif domain containing 10 Neighboring gene pre-mRNA splicing factor 6 Neighboring gene STARR-seq mESC enhancer starr_06756

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in negative regulation of miRNA transcription ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 512B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164597.2 → NP_001158069.1  zinc finger protein 512B isoform 4

    See identical proteins and their annotated locations for NP_001158069.1

    Status: VALIDATED

    Source sequence(s)
    AL844529
    Consensus CDS
    CCDS50855.1
    UniProtKB/TrEMBL
    B7ZCR6, Q6ZPW1
    Related
    ENSMUSP00000104417.3, ENSMUST00000108789.9
    Conserved Domains (2) summary
    PRK12323
    Location:170 → 425
    PRK12323; DNA polymerase III subunit gamma/tau
    sd00017
    Location:573 → 594
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_001409726.1 → NP_001396655.1  zinc finger protein 512B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL844529

  3. NM_001409728.1 → NP_001396657.1  zinc finger protein 512B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL844529

  4. NM_001409730.1 → NP_001396659.1  zinc finger protein 512B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL844529

  5. NM_001409731.1 → NP_001396660.1  zinc finger protein 512B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL844529
    Related
    ENSMUSP00000115601.2, ENSMUST00000128553.8

  6. NM_001409732.1 → NP_001396661.1  zinc finger protein 512B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL844529

  7. NM_001409733.1 → NP_001396662.1  zinc finger protein 512B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL844529
    UniProtKB/TrEMBL
    B7ZCR6

  8. NM_001409734.1 → NP_001396663.1  zinc finger protein 512B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL844529
    UniProtKB/TrEMBL
    B7ZCR6

  9. NM_001409735.1 → NP_001396664.1  zinc finger protein 512B isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL844529

  10. NM_001409736.1 → NP_001396665.1  zinc finger protein 512B isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL844529

  11. NM_001409737.1 → NP_001396666.1  zinc finger protein 512B isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL844529

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    181223925..181234572 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500650.5 → XP_006500713.1  zinc finger protein 512B isoform X3

    Conserved Domains (2) summary
    PHA03247
    Location:141 → 517
    PHA03247; large tegument protein UL36; Provisional
    sd00020
    Location:530 → 559
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_011239943.4 → XP_011238245.1  zinc finger protein 512B isoform X2

    Conserved Domains (2) summary
    PHA03247
    Location:141 → 436
    PHA03247; large tegument protein UL36; Provisional
    sd00020
    Location:533 → 562
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_375397.5 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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