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Tubd1 tubulin, delta 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287592, updated on 2-May-2024

Summary

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Official Symbol
Tubd1provided by RGD
Official Full Name
tubulin, delta 1provided by RGD
Primary source
RGD:1311967
See related
Ensembl:ENSRNOG00000053309 AllianceGenome:RGD:1311967
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable GTPase activity. Predicted to be involved in positive regulation of smoothened signaling pathway. Predicted to be located in cytosol and nucleoplasm. Orthologous to human TUBD1 (tubulin delta 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 56.7), Thymus (RPKM 54.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tubd1 in Genome Data Viewer
Location:
10q26
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (71865446..71888731)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (71367936..71391387)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (73865828..73886976)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene ring finger protein, transmembrane 1 Neighboring gene ribosomal protein S6 kinase B1 Neighboring gene microRNA 21 Neighboring gene vacuole membrane protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Tissue-specific expression and subcellular localisation of mammalian delta-tubulin. Smrzka OW, et al. Curr Biol, 2000 Apr 6. PMID 10753753
  2. CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog. Pusapati GV, et al. Dev Cell, 2018 Jan 8. PMID 29290584, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell projection organization IEA
Inferred from Electronic Annotation
more info
  
involved_in cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in microtubule-based process IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of smoothened signaling pathway ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in centriole IEA
Inferred from Electronic Annotation
more info
  
located_in cilium IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
tubulin delta chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105826.3 → NP_001099296.1  tubulin delta chain

    See identical proteins and their annotated locations for NP_001099296.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A0G2K6I6, A0A8I6G7A6, A6HHR1
    Related
    ENSRNOP00000082344.1, ENSRNOT00000094153.1
    Conserved Domains (1) summary
    cd02189
    Location:2 → 482
    delta_zeta_tubulin-like; The delta- and zeta-tubulin families

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    71865446..71888731
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039085560.2 → XP_038941488.1  tubulin delta chain isoform X6

    UniProtKB/TrEMBL
    A0A0G2K6I6, A0A8I6G7A6, A6HHR1
    Conserved Domains (1) summary
    cd02189
    Location:2 → 482
    delta_zeta_tubulin-like; The delta- and zeta-tubulin families

  2. XM_063268691.1 → XP_063124761.1  tubulin delta chain isoform X2

  3. XM_063268692.1 → XP_063124762.1  tubulin delta chain isoform X4

  4. XM_039085552.2 → XP_038941480.1  tubulin delta chain isoform X1

    UniProtKB/TrEMBL
    A0A0G2K6I6, A6HHR2
    Related
    ENSRNOP00000073829.2
    Conserved Domains (1) summary
    cd02189
    Location:2 → 452
    delta_zeta_tubulin-like; The delta- and zeta-tubulin families

  5. XM_039085551.2 → XP_038941479.1  tubulin delta chain isoform X1

    UniProtKB/TrEMBL
    A0A0G2K6I6, A6HHR2
    Conserved Domains (1) summary
    cd02189
    Location:2 → 452
    delta_zeta_tubulin-like; The delta- and zeta-tubulin families

  6. XM_039085553.2 → XP_038941481.1  tubulin delta chain isoform X1

    UniProtKB/TrEMBL
    A0A0G2K6I6, A6HHR2
    Conserved Domains (1) summary
    cd02189
    Location:2 → 452
    delta_zeta_tubulin-like; The delta- and zeta-tubulin families

  7. XM_039085556.2 → XP_038941484.1  tubulin delta chain isoform X3

    Conserved Domains (1) summary
    cd02189
    Location:1 → 333
    delta_zeta_tubulin-like; The delta- and zeta-tubulin families

  8. XM_039085558.2 → XP_038941486.1  tubulin delta chain isoform X5

    Conserved Domains (1) summary
    cd02189
    Location:8 → 261
    delta_zeta_tubulin-like; The delta- and zeta-tubulin families
Nucleotide Protein Strain
Heading Accession and Version

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