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Samd14 sterile alpha motif domain containing 14 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287637, updated on 5-Mar-2024

Summary

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Official Symbol
Samd14provided by RGD
Official Full Name
sterile alpha motif domain containing 14provided by RGD
Primary source
RGD:1306138
See related
Ensembl:ENSRNOG00000004155 AllianceGenome:RGD:1306138
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306138
Summary
Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization; calcium-mediated signaling; and neuron projection development. Predicted to be active in several cellular components, including actin cytoskeleton; dendrite; and postsynaptic density. Orthologous to human SAMD14 (sterile alpha motif domain containing 14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 31.4), Kidney (RPKM 4.2) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Samd14 in Genome Data Viewer
Location:
10q26
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (80453952..80469182)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (79957111..79972347)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (82820457..82838046)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene sarcoglycan, alpha Neighboring gene uncharacterized LOC102557019 Neighboring gene protein phosphatase 1, regulatory subunit 9B Neighboring gene uncharacterized LOC120095177 Neighboring gene pyruvate dehydrogenase kinase 2 Neighboring gene integrin subunit alpha 3 Neighboring gene uncharacterized LOC102546327

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Structural Analysis of Hippocampal Kinase Signal Transduction. McClatchy DB, et al. ACS Chem Neurosci, 2018 Dec 19. PMID 30053369, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC109312

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in calcium-mediated signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sterile alpha motif domain-containing protein 14
Names
SAM domain-containing protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024966.1 → NP_001020137.1  sterile alpha motif domain-containing protein 14

    See identical proteins and their annotated locations for NP_001020137.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091329
    UniProtKB/Swiss-Prot
    Q5BJU3
    UniProtKB/TrEMBL
    A0A8I6AB96
    Related
    ENSRNOP00000090621.1, ENSRNOT00000100588.1
    Conserved Domains (2) summary
    cd09512
    Location:321 → 386
    SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
    smart00454
    Location:323 → 386
    SAM; Sterile alpha motif

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    80453952..80469182
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039085587.2 → XP_038941515.1  sterile alpha motif domain-containing protein 14 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AB96, F1LN57
    Related
    ENSRNOP00000005519.8
    Conserved Domains (2) summary
    cd09512
    Location:323 → 388
    SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
    PHA03307
    Location:45 → 236
    PHA03307; transcriptional regulator ICP4; Provisional

  2. XM_039085588.2 → XP_038941516.1  sterile alpha motif domain-containing protein 14 isoform X2

    UniProtKB/TrEMBL
    A6HI78
    Conserved Domains (1) summary
    cd09512
    Location:309 → 374
    SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily

  3. XM_039085589.2 → XP_038941517.1  sterile alpha motif domain-containing protein 14 isoform X3

    UniProtKB/TrEMBL
    A0A8I6AB96
    Conserved Domains (1) summary
    cd09512
    Location:255 → 320
    SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BJU3.1 GenPept UniProtKB/Swiss-Prot:Q5BJU3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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