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Gltp glycolipid transfer protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 288707, updated on 5-Mar-2024

Summary

Official Symbol
Gltpprovided by RGD
Official Full Name
glycolipid transfer proteinprovided by RGD
Primary source
RGD:1564442
See related
Ensembl:ENSRNOG00000001192 AllianceGenome:RGD:1564442
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564442
Summary
Predicted to enable several functions, including ceramide 1-phosphate binding activity; ceramide 1-phosphate transfer activity; and identical protein binding activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be active in cytosol. Orthologous to human GLTP (glycolipid transfer protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 240.4), Lung (RPKM 159.5) and 9 other tissues See more
Orthologs
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Genomic context

See Gltp in Genome Data Viewer
Location:
12q16
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (47567797..47587949)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (41907168..41927321)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (47667556..47687708)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene GIT ArfGAP 2 Neighboring gene uncharacterized LOC102547088 Neighboring gene trichoplein, keratin filament binding Neighboring gene transient receptor potential cation channel, subfamily V, member 4 Neighboring gene family with sequence similarity 222, member A

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ceramide 1-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ceramide 1-phosphate transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glycolipid binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables lipid binding ISO
Inferred from Sequence Orthology
more info
 
enables lipid transfer activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in ceramide 1-phosphate transport IEA
Inferred from Electronic Annotation
more info
 
involved_in ceramide transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermembrane lipid transfer IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermembrane lipid transfer ISO
Inferred from Sequence Orthology
more info
 
involved_in response to immobilization stress IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
glycolipid transfer protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134413.1NP_001127885.1  glycolipid transfer protein

    See identical proteins and their annotated locations for NP_001127885.1

    Status: PROVISIONAL

    Source sequence(s)
    BC158884
    UniProtKB/Swiss-Prot
    B0BNM9
    Related
    ENSRNOP00000001581.5, ENSRNOT00000001581.7
    Conserved Domains (1) summary
    pfam08718
    Location:22163
    GLTP; Glycolipid transfer protein (GLTP)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    47567797..47587949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)