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Ints7 integrator complex subunit 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 289382, updated on 8-May-2024

Summary

Official Symbol
Ints7provided by RGD
Official Full Name
integrator complex subunit 7provided by RGD
Primary source
RGD:1308014
See related
AllianceGenome:RGD:1308014
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308014
Summary
Predicted to be involved in DNA damage checkpoint signaling; cellular response to ionizing radiation; and snRNA 3'-end processing. Predicted to be located in chromosome; cytoplasm; and nuclear body. Predicted to be part of integrator complex. Orthologous to human INTS7 (integrator complex subunit 7). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: suggests misassembly
Expression
Biased expression in Thymus (RPKM 207.7), Spleen (RPKM 126.6) and 9 other tissues See more
Orthologs
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Genomic context

Location:
13q27
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (105686208..105739609)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (103155123..103207953)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (110257571..110310413)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene stratifin, pseudogene 1 Neighboring gene denticleless E3 ubiquitin protein ligase homolog Neighboring gene ribosomal protein L12, pseudogene 10 Neighboring gene ribosomal protein S18, pseudogene 10 Neighboring gene ribosomal protein L37 like 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to ionizing radiation ISO
Inferred from Sequence Orthology
more info
 
involved_in snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in snRNA processing ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in chromosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of integrator complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of integrator complex ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
integrator complex subunit 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191675.1NP_001178604.1  integrator complex subunit 7

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000013
    UniProtKB/TrEMBL
    A6JH00

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    105686208..105739609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063272191.1XP_063128261.1  integrator complex subunit 7 isoform X1