Tnfrsf19 TNF receptor superfamily member 19 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tnfrsf19provided by RGD
Official Full Name: TNF receptor superfamily member 19provided by RGD
Primary source: RGD:1564996
See related: Ensembl:ENSRNOG00000014265 AllianceGenome:RGD:1564996
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564996
Summary: Predicted to enable signaling receptor activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of JNK cascade. Predicted to act upstream of or within hair follicle development. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human TNFRSF19 (TNF receptor superfamily member 19). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Adrenal (RPKM 89.0), Brain (RPKM 82.3) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 15p12

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (39268305..39334566, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (35092206..35158472, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (41249820..41316203, complement)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

the association of RhoGDIalpha with TROY contributed to TROY-dependent RhoA activation and neurite outgrowth inhibition after Nogo-66 stimulation.
Title: TROY interacts with Rho guanine nucleotide dissociation inhibitor α (RhoGDIα) to mediate Nogo-induced inhibition of neurite outgrowth.

Submit: New GeneRIF Correction

General gene information

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Markers

BF420646 (e-PCR)
- UniSTS:248690

BE102295 (e-PCR)
- UniSTS:244119

RH138833 (e-PCR)
- UniSTS:220920

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables signaling receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within hair follicle development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of JNK cascade	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of canonical NF-kappaB signal transduction	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of canonical NF-kappaB signal transduction	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: tumor necrosis factor receptor superfamily member 19

Names: tumor necrosis factor receptor superfamily, member 19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.