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B3gnt3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 290638, updated on 11-Apr-2024

Summary

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Official Symbol
B3gnt3provided by RGD
Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3provided by RGD
Primary source
RGD:1305151
See related
Ensembl:ENSRNOG00000018764 AllianceGenome:RGD:1305151
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane. Orthologous to human B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Uterus (RPKM 3.4), Adrenal (RPKM 2.9) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
16p14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (18434114..18444851, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (18401405..18410821, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (20123948..20133482, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene unc-13 homolog A Neighboring gene Janus kinase 3 Neighboring gene insulin-like 3 Neighboring gene uncharacterized LOC108348388 Neighboring gene FCH and mu domain containing endocytic adaptor 1 Neighboring gene uncharacterized LOC134482326

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase family. Shiraishi N, et al. J Biol Chem, 2001 Feb 2. PMID 11042166
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in poly-N-acetyllactosamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in poly-N-acetyllactosamine biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
NP_001099538.1
XP_017455515.1
XP_038950229.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106068.1 → NP_001099538.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 precursor

    See identical proteins and their annotated locations for NP_001099538.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474031
    UniProtKB/TrEMBL
    A6K9X8, D3ZX31
    Related
    ENSRNOP00000025362.3, ENSRNOT00000025363.4
    Conserved Domains (1) summary
    cl21608
    Location:119 → 308
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    18434114..18444851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017600026.3 → XP_017455515.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 isoform X2

    UniProtKB/TrEMBL
    A6K9X8, D3ZX31
    Conserved Domains (1) summary
    cl21608
    Location:119 → 308
    Galactosyl_T; Galactosyltransferase

  2. XM_039094301.2 → XP_038950229.2  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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