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Sugp1 SURP and G patch domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 290666, updated on 2-May-2024

Summary

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Official Symbol
Sugp1provided by RGD
Official Full Name
SURP and G patch domain containing 1provided by RGD
Primary source
RGD:1310496
See related
Ensembl:ENSRNOG00000052111 AllianceGenome:RGD:1310496
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Sf4
Summary
Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of spliceosomal complex. Orthologous to human SUGP1 (SURP and G-patch domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 116.8), Adrenal (RPKM 105.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Sugp1 in Genome Data Viewer
Location:
16p14
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (19386588..19417460, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (19352659..19383533, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (21100923..21131795, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene hyaluronan and proteoglycan link protein 4 Neighboring gene transmembrane 6 superfamily member 2 Neighboring gene MAU2 sister chromatid cohesion factor Neighboring gene GATA zinc finger domain containing 2A Neighboring gene testis-specific serine kinase 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SURP and G-patch domain-containing protein 1
Names
splicing factor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011920.1 → NP_001011920.1  SURP and G-patch domain-containing protein 1

    See identical proteins and their annotated locations for NP_001011920.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079341
    UniProtKB/Swiss-Prot
    Q68FU8
    UniProtKB/TrEMBL
    A0A8L2R876, A6KA93
    Related
    ENSRNOP00000082578.1, ENSRNOT00000110921.1
    Conserved Domains (2) summary
    pfam01585
    Location:562 → 606
    G-patch; G-patch domain
    pfam01805
    Location:187 → 238
    Surp; Surp module

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    19386588..19417460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039094335.2 → XP_038950263.1  SURP and G-patch domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8L2R876
    Related
    ENSRNOP00000072874.2
    Conserved Domains (3) summary
    PHA02682
    Location:285 → 379
    PHA02682; ORF080 virion core protein; Provisional
    pfam01585
    Location:543 → 587
    G-patch; G-patch domain
    pfam01805
    Location:168 → 219
    Surp; Surp module
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q68FU8.1 GenPept UniProtKB/Swiss-Prot:Q68FU8

Gene LinkOut

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