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Fam13b family with sequence similarity 13, member B [ Rattus norvegicus (Norway rat) ]

Gene ID: 291694, updated on 6-Jun-2024

Summary

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Official Symbol
Fam13bprovided by RGD
Official Full Name
family with sequence similarity 13, member Bprovided by RGD
Primary source
RGD:1310484
See related
Ensembl:ENSRNOG00000020384 AllianceGenome:RGD:1310484
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam13b1; RGD1310484
Summary
Predicted to be involved in signal transduction. Orthologous to human FAM13B (family with sequence similarity 13 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 207.8), Spleen (RPKM 196.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam13b in Genome Data Viewer
Location:
18p12
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (26314440..26395260, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (26040285..26107112, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (27223345..27304462, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene signal recognition particle 19, pseudogene 2 Neighboring gene receptor accessory protein 5 Neighboring gene polycystin 2 like 2, transient receptor potential cation channel Neighboring gene Set nuclear proto-oncogene, pseudogene 8 Neighboring gene Wnt family member 8A Neighboring gene uncharacterized LOC134482927 Neighboring gene NME/NM23 family member 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein FAM13B
Names
family with sequence similarity 13, member B1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106158.1 → NP_001099628.1  protein FAM13B

    See identical proteins and their annotated locations for NP_001099628.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473974
    UniProtKB/TrEMBL
    A0A8I6G832, A6J2U4, D3ZJY0
    Related
    ENSRNOP00000027663.4, ENSRNOT00000027663.6
    Conserved Domains (1) summary
    cd04393
    Location:19 → 205
    RhoGAP_FAM13A1a; RhoGAP_FAM13A1a: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    26314440..26395260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063277238.1 → XP_063133308.1  protein FAM13B isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZRM9, A0A8I6G832

  2. XM_063277236.1 → XP_063133306.1  protein FAM13B isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZRM9, A0A8I6G832

  3. XM_063277247.1 → XP_063133317.1  protein FAM13B isoform X5

    UniProtKB/TrEMBL
    A0A8I6G832

  4. XM_063277252.1 → XP_063133322.1  protein FAM13B isoform X6

    UniProtKB/TrEMBL
    A0A8I6A1J8, A0A8I6G832

  5. XM_063277239.1 → XP_063133309.1  protein FAM13B isoform X2

    UniProtKB/TrEMBL
    A0A8I6G832, A6J2U4, D3ZJY0

  6. XM_063277240.1 → XP_063133310.1  protein FAM13B isoform X2

    UniProtKB/TrEMBL
    A0A8I6G832, A6J2U4, D3ZJY0

  7. XM_063277245.1 → XP_063133315.1  protein FAM13B isoform X2

    UniProtKB/TrEMBL
    A0A8I6G832, A6J2U4, D3ZJY0

  8. XM_063277250.1 → XP_063133320.1  protein FAM13B isoform X6

    UniProtKB/TrEMBL
    A0A8I6A1J8, A0A8I6G832

  9. XM_063277243.1 → XP_063133313.1  protein FAM13B isoform X2

    UniProtKB/TrEMBL
    A0A8I6G832, A6J2U4, D3ZJY0

  10. XM_063277235.1 → XP_063133305.1  protein FAM13B isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZRM9, A0A8I6G832

  11. XM_063277246.1 → XP_063133316.1  protein FAM13B isoform X2

    UniProtKB/TrEMBL
    A0A8I6G832, A6J2U4, D3ZJY0

  12. XM_063277251.1 → XP_063133321.1  protein FAM13B isoform X6

    UniProtKB/TrEMBL
    A0A8I6A1J8, A0A8I6G832

  13. XM_039096730.2 → XP_038952658.1  protein FAM13B isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZRM9, A0A8I6G832
    Conserved Domains (2) summary
    cd04393
    Location:19 → 205
    RhoGAP_FAM13A1a; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound ...
    cl26235
    Location:813 → 852
    RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

  14. XM_063277241.1 → XP_063133311.1  protein FAM13B isoform X2

    UniProtKB/TrEMBL
    A0A8I6G832, A6J2U4, D3ZJY0

  15. XM_063277249.1 → XP_063133319.1  protein FAM13B isoform X6

    UniProtKB/TrEMBL
    A0A8I6A1J8, A0A8I6G832

  16. XM_039096731.2 → XP_038952659.1  protein FAM13B isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZRM9, A0A8I6G832
    Conserved Domains (2) summary
    cd04393
    Location:19 → 205
    RhoGAP_FAM13A1a; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound ...
    cl26235
    Location:813 → 852
    RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

  17. XM_039096733.2 → XP_038952661.1  protein FAM13B isoform X8

    Conserved Domains (1) summary
    cl26235
    Location:623 → 662
    RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

  18. XM_039096732.2 → XP_038952660.1  protein FAM13B isoform X8

    Conserved Domains (1) summary
    cl26235
    Location:623 → 662
    RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

  19. XM_063277253.1 → XP_063133323.1  protein FAM13B isoform X7

    UniProtKB/TrEMBL
    A0A8I6G832

  20. XM_008772033.4 → XP_008770255.1  protein FAM13B isoform X5

    UniProtKB/TrEMBL
    A0A8I6G832
    Conserved Domains (1) summary
    cd04393
    Location:19 → 205
    RhoGAP_FAM13A1a; RhoGAP_FAM13A1a: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active ...

  21. XM_063277248.1 → XP_063133318.1  protein FAM13B isoform X6

    UniProtKB/TrEMBL
    A0A8I6A1J8, A0A8I6G832

  22. XM_008772031.4 → XP_008770253.1  protein FAM13B isoform X3

    UniProtKB/TrEMBL
    A0A8I6G832
    Conserved Domains (1) summary
    cd04393
    Location:19 → 205
    RhoGAP_FAM13A1a; RhoGAP_FAM13A1a: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active ...

  23. XM_008772032.4 → XP_008770254.1  protein FAM13B isoform X4

    UniProtKB/TrEMBL
    A0A8I6G832
    Conserved Domains (1) summary
    cd04393
    Location:19 → 205
    RhoGAP_FAM13A1a; RhoGAP_FAM13A1a: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active ...

  24. XM_017600914.3 → XP_017456403.1  protein FAM13B isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZRM9, A0A8I6G832
    Related
    ENSRNOP00000079749.1
    Conserved Domains (2) summary
    cd04393
    Location:19 → 205
    RhoGAP_FAM13A1a; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of FAM13A1, isoform a-like proteins. The function of FAM13A1a is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their GTP-bound ...
    cl26235
    Location:813 → 852
    RecQL4_SLD2_NTD; N-terminal homeodomain-like domain of metazoan RecQ protein-like 4 (RecQL4), fungal DNA replication regulator SLD2 and similar proteins

  25. XM_063277242.1 → XP_063133312.1  protein FAM13B isoform X2

    UniProtKB/TrEMBL
    A0A8I6G832, A6J2U4, D3ZJY0

  26. XM_063277237.1 → XP_063133307.1  protein FAM13B isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZRM9, A0A8I6G832

  27. XM_063277244.1 → XP_063133314.1  protein FAM13B isoform X2

    UniProtKB/TrEMBL
    A0A8I6G832, A6J2U4, D3ZJY0

  28. XM_039096734.1 → XP_038952662.1  protein FAM13B isoform X9

Nucleotide Protein Strain
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