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Enkd1 enkurin domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291975, updated on 5-Mar-2024

Summary

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Official Symbol
Enkd1provided by RGD
Official Full Name
enkurin domain containing 1provided by RGD
Primary source
RGD:1307357
See related
Ensembl:ENSRNOG00000024364 AllianceGenome:RGD:1307357
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307357
Summary
Predicted to be located in ciliary base and microtubule cytoskeleton. Predicted to be active in cytoplasmic microtubule. Orthologous to human ENKD1 (enkurin domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 64.0), Kidney (RPKM 34.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Enkd1 in Genome Data Viewer
Location:
19q12
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (50501963..50506447, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (33592074..33596552, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (37670624..37675101, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene CCCTC-binding factor like 2 Neighboring gene CCCTC-binding factor Neighboring gene capping protein regulator and myosin 1 linker 2 Neighboring gene similar to human chromosome 16 open reading frame 86 Neighboring gene par-6 family cell polarity regulator alpha Neighboring gene ACD, shelterin complex subunit and telomerase recruitment factor Neighboring gene Gfo/Idh/MocA-like oxidoreductase domain containing 2 Neighboring gene small nuclear ribonucleoprotein polypeptide G, pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis. Fong KW, et al. J Cell Sci, 2013 Feb 1. PMID 23264731, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables alpha-tubulin binding ISO
Inferred from Sequence Orthology
more info
  
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in establishment of mitotic spindle orientation ISO
Inferred from Sequence Orthology
more info
  
involved_in motile cilium assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in non-motile cilium assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in 9+0 non-motile cilium ISO
Inferred from Sequence Orthology
more info
  
located_in centriole ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
  
located_in ciliary base ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytoplasmic microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
  
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
enkurin domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106180.1 → NP_001099650.1  enkurin domain-containing protein 1

    See identical proteins and their annotated locations for NP_001099650.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473972
    UniProtKB/TrEMBL
    A6IYS0, D4A243
    Conserved Domains (1) summary
    pfam13864
    Location:243 → 337
    Enkurin; Calmodulin-binding

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    50501963..50506447 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006255476.5 → XP_006255538.1  enkurin domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006255538.1

    UniProtKB/TrEMBL
    A6IYS0, D4A243
    Conserved Domains (1) summary
    pfam13864
    Location:243 → 337
    Enkurin; Calmodulin-binding

  2. XM_006255478.5 → XP_006255540.1  enkurin domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006255540.1

    UniProtKB/TrEMBL
    A6IYS0, D4A243
    Related
    ENSRNOP00000033730.4
    Conserved Domains (1) summary
    pfam13864
    Location:243 → 337
    Enkurin; Calmodulin-binding

  3. XM_006255477.5 → XP_006255539.1  enkurin domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006255539.1

    UniProtKB/TrEMBL
    A6IYS0, D4A243
    Conserved Domains (1) summary
    pfam13864
    Location:243 → 337
    Enkurin; Calmodulin-binding

  4. XM_039097617.2 → XP_038953545.1  enkurin domain-containing protein 1 isoform X3

  5. XM_063277925.1 → XP_063133995.1  enkurin domain-containing protein 1 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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