Ceacam20 CEA cell adhesion molecule 20 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ceacam20provided by RGD
Official Full Name: CEA cell adhesion molecule 20provided by RGD
Primary source: RGD:1311281
See related: Ensembl:ENSRNOG00000019260 AllianceGenome:RGD:1311281
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1311281
Summary: Predicted to be involved in positive regulation of cytokine production. Predicted to act upstream of or within response to bacterium. Predicted to be located in apical plasma membrane and microvillus membrane. Orthologous to human CEACAM20 (CEA cell adhesion molecule 20). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward (RPKM 11.1) See more
Orthologs: human mouse all
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Genomic context

Location:: 1q21

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (88750010..88771679)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (79622077..79643782)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (80880856..80912082)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein tyrosine kinase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in positive regulation of cytokine production	ISO Inferred from Sequence Orthology more info
involved_in regulation of immune system process	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to bacterium	ISO Inferred from Sequence Orthology more info
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	ISO Inferred from Sequence Orthology more info
is_active_in cell surface	IBA Inferred from Biological aspect of Ancestor more info
located_in microvillus membrane	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: carcinoembryonic antigen-related cell adhesion molecule 20

Names: CEA-related cell adhesion molecule 20; carcinoembryonic antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001170324.1 → NP_001163795.1 carcinoembryonic antigen-related cell adhesion molecule 20 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

D4ADQ8

Related

ENSRNOP00000026060.7, ENSRNOT00000026060.8

Conserved Domains (3) summary

smart00408
Location:352 → 406

IGc2; Immunoglobulin C-2 Type

smart00410
Location:158 → 233

IG_like; Immunoglobulin like

cl11960
Location:250 → 327

Ig; Immunoglobulin domain