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Pdzd4 PDZ domain containing 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 293856, updated on 13-Apr-2024

Summary

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Official Symbol
Pdzd4provided by RGD
Official Full Name
PDZ domain containing 4provided by RGD
Primary source
RGD:1561214
See related
Ensembl:ENSRNOG00000056174 AllianceGenome:RGD:1561214
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561214
Summary
Orthologous to human PDZD4 (PDZ domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 54.8), Spleen (RPKM 7.3) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Pdzd4 in Genome Data Viewer
Location:
Xq37
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (156681717..156712031, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (151530390..151560779, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (156963343..156993591)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma Neighboring gene signal sequence receptor subunit 4 Neighboring gene L1 cell adhesion molecule Neighboring gene arginine vasopressin receptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
PDZ domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135836.1 → NP_001129308.1  PDZ domain-containing protein 4 isoform 2

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000021
    UniProtKB/TrEMBL
    A6KRU8
    Conserved Domains (1) summary
    cd00992
    Location:130 → 212
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  2. NM_001414724.1 → NP_001401653.1  PDZ domain-containing protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021
    UniProtKB/TrEMBL
    D3ZLI9
    Related
    ENSRNOP00000072313.2, ENSRNOT00000077109.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    156681717..156712031 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039099532.2 → XP_038955460.1  PDZ domain-containing protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZXV3, A0A8I6AJE7
    Related
    ENSRNOP00000093710.1

  2. XM_006229565.5 → XP_006229627.1  PDZ domain-containing protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZXV3, A0A8I6AHV5
    Related
    ENSRNOP00000088024.1
    Conserved Domains (1) summary
    cd00992
    Location:19 → 103
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  3. XM_039099533.2 → XP_038955461.1  PDZ domain-containing protein 4 isoform X4

  4. XM_006229564.5 → XP_006229626.1  PDZ domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A6KRU8
Nucleotide Protein Strain
Heading Accession and Version

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