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Mlana melan-A [ Rattus norvegicus (Norway rat) ]

Gene ID: 293890, updated on 3-Apr-2024

Summary

Official Symbol
Mlanaprovided by RGD
Official Full Name
melan-Aprovided by RGD
Primary source
RGD:1306525
See related
Ensembl:ENSRNOG00000036608 AllianceGenome:RGD:1306525
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in Golgi apparatus. Predicted to be active in endoplasmic reticulum membrane; melanosome; and trans-Golgi network. Orthologous to human MLANA (melan-A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 11.8) and Uterus (RPKM 7.3) See more
Orthologs
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Genomic context

Location:
1q52
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (236883075..236897693)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (227469537..227483343)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (247869756..247883558)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120100017 Neighboring gene uncharacterized LOC120100018 Neighboring gene bromodomain containing 10 Neighboring gene 60S ribosomal protein L7a pseudogene Neighboring gene RAN binding protein 6

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in melanosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in melanosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
melanoma antigen recognized by T-cells 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106348.1NP_001099818.1  melanoma antigen recognized by T-cells 1

    See identical proteins and their annotated locations for NP_001099818.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473953
    UniProtKB/TrEMBL
    A6I0X0, D3ZWI9
    Related
    ENSRNOP00000051645.2, ENSRNOT00000054764.4
    Conserved Domains (1) summary
    pfam14991
    Location:2116
    MLANA; Protein melan-A

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    236883075..236897693
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063287038.1XP_063143108.1  melanoma antigen recognized by T-cells 1 isoform X1

    UniProtKB/TrEMBL
    A6I0X0, D3ZWI9