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Cspg4b chondroitin sulfate proteoglycan 4B [ Rattus norvegicus (Norway rat) ]

Gene ID: 294747, updated on 30-Mar-2024

Summary

Official Symbol
Cspg4bprovided by RGD
Official Full Name
chondroitin sulfate proteoglycan 4Bprovided by RGD
Primary source
RGD:1561161
See related
Ensembl:ENSRNOG00000039582 AllianceGenome:RGD:1561161
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561161
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 146.9), Muscle (RPKM 98.0) and 8 other tissues See more
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Genomic context

Location:
2q14
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (46673142..46743288)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (44939807..45008284)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (45182391..45241179)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485841 Neighboring gene endothelial cell-specific molecule 1 Neighboring gene uncharacterized LOC120100709 Neighboring gene uncharacterized LOC134485842

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
chondroitin sulfate proteoglycan 4B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134510.2NP_001127982.2  chondroitin sulfate proteoglycan 4B precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A0G2K8H2, D4AE71
    Related
    ENSRNOP00000074606.1, ENSRNOT00000085826.2
    Conserved Domains (2) summary
    cd00110
    Location:26175
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam16184
    Location:12991406
    Cadherin_3; Cadherin-like

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    46673142..46743288
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039101941.2XP_038957869.1  chondroitin sulfate proteoglycan 4B isoform X4

    UniProtKB/TrEMBL
    A6I5R3
    Conserved Domains (2) summary
    cd00110
    Location:26175
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam16184
    Location:12991406
    Cadherin_3; Cadherin-like
  2. XM_039101939.2XP_038957867.1  chondroitin sulfate proteoglycan 4B isoform X1

    UniProtKB/TrEMBL
    D4AE71
    Conserved Domains (2) summary
    cd00110
    Location:26175
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam16184
    Location:14971602
    Cadherin_3; Cadherin-like
  3. XM_039101942.2XP_038957870.1  chondroitin sulfate proteoglycan 4B isoform X5

    Conserved Domains (2) summary
    pfam16184
    Location:112219
    Cadherin_3; Cadherin-like
    cl22861
    Location:2682
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
  4. XM_063281517.1XP_063137587.1  chondroitin sulfate proteoglycan 4B isoform X3

  5. XM_039101940.2XP_038957868.1  chondroitin sulfate proteoglycan 4B isoform X2

    UniProtKB/TrEMBL
    D4AE71
    Conserved Domains (1) summary
    pfam16184
    Location:9941101
    Cadherin_3; Cadherin-like