Pabpc4l poly(A) binding protein, cytoplasmic 4-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pabpc4lprovided by RGD
Official Full Name: poly(A) binding protein, cytoplasmic 4-likeprovided by RGD
Primary source: RGD:1559517
See related: Ensembl:ENSRNOG00000029749 AllianceGenome:RGD:1559517
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1559517
Summary: Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasmic stress granule; cytosol; and nucleus. Orthologous to human PABPC4L (poly(A) binding protein cytoplasmic 4 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Uterus (RPKM 11.4), Adrenal (RPKM 10.5) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q26

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (131743939..131745929, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (129807755..129809745, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (130656212..130658202, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables mRNA 3'-UTR binding	IBA Inferred from Biological aspect of Ancestor more info
enables poly(A) binding	IBA Inferred from Biological aspect of Ancestor more info
enables poly(U) RNA binding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasmic stress granule	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: polyadenylate-binding protein 4-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106429.1 → NP_001099899.1 polyadenylate-binding protein 4-like

See identical proteins and their annotated locations for NP_001099899.1

Status: PROVISIONAL

Source sequence(s)

CH474091

UniProtKB/TrEMBL

A6KQP8, D3ZGA4

Related

ENSRNOP00000017012.4, ENSRNOT00000017012.5

Conserved Domains (5) summary

cd12378
Location:11 → 89

RRM1_I_PABPs; RNA recognition motif 1 in type I polyadenylate-binding proteins

cd12379
Location:96 → 171

RRM2_I_PABPs; RNA recognition motif 2 found in type I polyadenylate-binding proteins

cd12380
Location:189 → 268

RRM3_I_PABPs; RNA recognition motif 3 found in type I polyadenylate-binding proteins

TIGR01661
Location:11 → 262

ELAV_HUD_SF; ELAV/HuD family splicing factor

cl17169
Location:293 → 369

RRM_SF; RNA recognition motif (RRM) superfamily