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Emcn endomucin [ Rattus norvegicus (Norway rat) ]

Gene ID: 295490, updated on 5-Mar-2024

Summary

Official Symbol
Emcnprovided by RGD
Official Full Name
endomucinprovided by RGD
Primary source
RGD:1303218
See related
Ensembl:ENSRNOG00000022910 AllianceGenome:RGD:1303218
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable carbohydrate binding activity. Predicted to be involved in angiogenesis; cell-cell adhesion; and regulation of cell adhesion. Predicted to act upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in plasma membrane. Orthologous to human EMCN (endomucin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Lung (RPKM 509.8), Kidney (RPKM 368.8) and 8 other tissues See more
Orthologs
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Genomic context

See Emcn in Genome Data Viewer
Location:
2q43
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (228564445..228644370)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (225891100..225970932)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (242634319..242715489)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene protein kinase C and casein kinase substrate in neurons 3, pseudogene 1 Neighboring gene uncharacterized LOC120100622 Neighboring gene uncharacterized LOC120100949 Neighboring gene uncharacterized LOC134485976 Neighboring gene DNA-damage-inducible transcript 4-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC94175

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables carbohydrate binding ISO
Inferred from Sequence Orthology
more info
 
enables carbohydrate binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in angiogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in angiogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cell-cell adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within hematopoietic stem cell homeostasis ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004228.1NP_001004228.1  endomucin precursor

    See identical proteins and their annotated locations for NP_001004228.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079155
    UniProtKB/Swiss-Prot
    Q6AY82
    UniProtKB/TrEMBL
    A6HW00
    Related
    ENSRNOP00000033031.3, ENSRNOT00000035700.4
    Conserved Domains (1) summary
    pfam07010
    Location:1250
    Endomucin; Endomucin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    228564445..228644370
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281668.1XP_063137738.1  endomucin isoform X1

  2. XM_063281669.1XP_063137739.1  endomucin isoform X2