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Tex261 testis expressed 261 [ Rattus norvegicus (Norway rat) ]

Gene ID: 297392, updated on 2-May-2024

Summary

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Official Symbol
Tex261provided by RGD
Official Full Name
testis expressed 261provided by RGD
Primary source
RGD:1305851
See related
AllianceGenome:RGD:1305851
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable COPII receptor activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to act upstream of or within positive regulation of apoptotic process. Predicted to be active in COPII-coated ER to Golgi transport vesicle. Predicted to be integral component of Golgi membrane and integral component of endoplasmic reticulum membrane. Orthologous to human TEX261 (testis expressed 261). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 155.1), Heart (RPKM 149.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tex261 in Genome Data Viewer
Location:
4q34
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (117813050..117818408, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (116253547..116260730, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (115446830..115454035, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene ATPase H+ transporting V1 subunit B1 Neighboring gene ankyrin repeat domain 53 Neighboring gene uncharacterized LOC134486595 Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene N-acetylglucosamine kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Tex261 modulates the excitotoxic cell death induced by N-methyl-D-aspartate (NMDA) receptor activation. Taniura H, et al. Biochem Biophys Res Commun, 2007 Nov 3. PMID 17803966
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC109238

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables COPII receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables COPII receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein TEX261
Names
testis expressed gene 261

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017537.1 → NP_001017537.1  protein TEX261

    See identical proteins and their annotated locations for NP_001017537.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091302
    UniProtKB/Swiss-Prot
    Q5BJW3
    UniProtKB/TrEMBL
    A0A8L2QVX6, A6IAP6
    Conserved Domains (1) summary
    pfam04148
    Location:1 → 186
    Erv26; Transmembrane adaptor Erv26

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    117813050..117818408 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017592548.3 → XP_017448037.1  protein TEX261 isoform X2

    Conserved Domains (1) summary
    pfam04148
    Location:1 → 147
    Erv26; Transmembrane adaptor Erv26

  2. XM_008763059.4 → XP_008761281.1  protein TEX261 isoform X1

    UniProtKB/TrEMBL
    A0A8L2QVX6
    Conserved Domains (1) summary
    pfam04148
    Location:1 → 194
    Erv26; Transmembrane adaptor Erv26

  3. XM_039107343.2 → XP_038963271.1  protein TEX261 isoform X2

    Conserved Domains (1) summary
    pfam04148
    Location:1 → 147
    Erv26; Transmembrane adaptor Erv26

  4. XM_008763061.4 → XP_008761283.1  protein TEX261 isoform X2

    See identical proteins and their annotated locations for XP_008761283.1

    Conserved Domains (1) summary
    pfam04148
    Location:1 → 147
    Erv26; Transmembrane adaptor Erv26
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BJW3.1 GenPept UniProtKB/Swiss-Prot:Q5BJW3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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