Zdhhc21 zinc finger DHHC-type palmitoyltransferase 21 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zdhhc21provided by RGD
Official Full Name: zinc finger DHHC-type palmitoyltransferase 21provided by RGD
Primary source: RGD:1305750
See related: Ensembl:ENSRNOG00000010484 AllianceGenome:RGD:1305750
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in several processes, including peptidyl-L-cysteine S-palmitoylation; regulation of establishment of endothelial barrier; and regulation of vascular associated smooth muscle contraction. Predicted to act upstream of or within hair follicle development; protein palmitoylation; and sebaceous gland development. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC21 (zinc finger DHHC-type palmitoyltransferase 21). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 87.5), Brain (RPKM 81.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q31

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (102273561..102333174, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (97227621..97286866, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (100924621..100983412, complement)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables palmitoyltransferase activity	ISO Inferred from Sequence Orthology more info
enables protein-cysteine S-palmitoyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein-cysteine S-palmitoyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in adrenergic receptor signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within hair follicle development	ISO Inferred from Sequence Orthology more info
involved_in peptidyl-L-cysteine S-palmitoylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein targeting to membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of establishment of endothelial barrier	ISO Inferred from Sequence Orthology more info
involved_in regulation of leukocyte adhesion to arterial endothelial cell	ISO Inferred from Sequence Orthology more info
involved_in regulation of vascular associated smooth muscle contraction	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within sebaceous gland development	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: palmitoyltransferase ZDHHC21

Names: probable palmitoyltransferase ZDHHC21; zinc finger, DHHC domain containing 21; zinc finger, DHHC-type containing 21

NP_001034098.1

EC 2.3.1.225

XP_008761988.1

EC 2.3.1.225

XP_008761989.1

EC 2.3.1.225

XP_008761990.1

EC 2.3.1.225

XP_038965434.1

EC 2.3.1.225

XP_038965435.1

EC 2.3.1.225

XP_063143436.1

EC 2.3.1.225

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.