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Mtfr1l mitochondrial fission regulator 1-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 298549, updated on 5-Mar-2024

Summary

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Official Symbol
Mtfr1lprovided by RGD
Official Full Name
mitochondrial fission regulator 1-likeprovided by RGD
Primary source
RGD:1305453
See related
Ensembl:ENSRNOG00000016937 AllianceGenome:RGD:1305453
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam54b; RGD1305453
Summary
Predicted to be involved in aerobic respiration and mitochondrial fission. Predicted to be active in mitochondrion. Orthologous to human MTFR1L (mitochondrial fission regulator 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 1112.3), Heart (RPKM 1060.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mtfr1l in Genome Data Viewer
Location:
5q36
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (152020617..152030417, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (146736927..146746891, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (152736580..152746683, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene progestin and adipoQ receptor family member 7 Neighboring gene aurora kinase A and ninein interacting protein Neighboring gene selenoprotein N Neighboring gene mannosidase, alpha, class 1C, member 1 Neighboring gene transfer RNA proline (anticodon AGG) 56

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in aerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in aerobic respiration IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial fission IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial fission IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial fission regulator 1-like
Names
family with sequence similarity 54, member B
protein FAM54B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013935.1 → NP_001013957.1  mitochondrial fission regulator 1-like

    See identical proteins and their annotated locations for NP_001013957.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083692
    UniProtKB/Swiss-Prot
    Q5XII9
    UniProtKB/TrEMBL
    A0A8L2QC55, A6IT30
    Conserved Domains (1) summary
    pfam05308
    Location:9 → 250
    Mito_fiss_reg; Mitochondrial fission regulator

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    152020617..152030417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006239125.5 → XP_006239187.1  mitochondrial fission regulator 1-like isoform X1

    See identical proteins and their annotated locations for XP_006239187.1

    UniProtKB/Swiss-Prot
    Q5XII9
    UniProtKB/TrEMBL
    A0A8L2QC55, A6IT30
    Related
    ENSRNOP00000022908.5
    Conserved Domains (1) summary
    pfam05308
    Location:9 → 250
    Mito_fiss_reg; Mitochondrial fission regulator

  2. XM_039109639.2 → XP_038965567.1  mitochondrial fission regulator 1-like isoform X2

    UniProtKB/TrEMBL
    A0A8I6ABW1, A0A8L2QC55
    Related
    ENSRNOP00000090892.1
    Conserved Domains (1) summary
    pfam05308
    Location:9 → 238
    Mito_fiss_reg; Mitochondrial fission regulator
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XII9.1 GenPept UniProtKB/Swiss-Prot:Q5XII9

Gene LinkOut

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