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Ypel5 yippee-like 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298792, updated on 3-Apr-2024

Summary

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Symbol
Ypel5provided by RGD
Full Name
yippee-like 5provided by RGD
Primary source
RGD:1309657
See related
Ensembl:ENSRNOG00000026742 AllianceGenome:RGD:1309657
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable metal ion binding activity. Predicted to be part of ubiquitin ligase complex. Orthologous to human YPEL5 (yippee like 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 469.9), Brain (RPKM 331.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
6q14
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (28408079..28423536, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (22656284..22671741, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (24069351..24084758)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351184 Neighboring gene LBH regulator of WNT signaling pathway Neighboring gene uncharacterized LOC103692567 Neighboring gene uncharacterized LOC108351183 Neighboring gene ALK receptor tyrosine kinase Neighboring gene stratifin like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation. Lampert F, et al. Elife, 2018 Jun 18. PMID 29911972, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein yippee-like 5
NP_001030298.1
XP_008762730.1
XP_008762731.1
XP_008762732.1
XP_038967832.1
XP_038967833.1
XP_038967835.1
XP_063117688.1
XP_063117689.1
XP_063117690.1
XP_063117692.1
XP_063117693.1
XP_063117694.1
XP_063117695.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001035221.1 → NP_001030298.1  protein yippee-like 5

    See identical proteins and their annotated locations for NP_001030298.1

    Status: PROVISIONAL

    Source sequence(s)
    BC105836, CB584328
    UniProtKB/TrEMBL
    A6HA10, D4A4Q3
    Related
    ENSRNOP00000038910.4, ENSRNOT00000035362.5
    Conserved Domains (1) summary
    cl13152
    Location:15 → 107
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    28408079..28423536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039111905.2 → XP_038967833.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 107
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  2. XM_039111907.2 → XP_038967835.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 107
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  3. XM_008764508.3 → XP_008762730.1  protein yippee-like 5 isoform X1

    See identical proteins and their annotated locations for XP_008762730.1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 107
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  4. XM_063261622.1 → XP_063117692.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3

  5. XM_063261625.1 → XP_063117695.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3

  6. XM_008764510.4 → XP_008762732.1  protein yippee-like 5 isoform X1

    See identical proteins and their annotated locations for XP_008762732.1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 107
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  7. XM_008764509.4 → XP_008762731.1  protein yippee-like 5 isoform X1

    See identical proteins and their annotated locations for XP_008762731.1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 107
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  8. XM_063261620.1 → XP_063117690.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3

  9. XM_063261618.1 → XP_063117688.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3

  10. XM_063261623.1 → XP_063117693.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3

  11. XM_039111904.2 → XP_038967832.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 107
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  12. XM_063261624.1 → XP_063117694.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3

  13. XM_063261619.1 → XP_063117689.1  protein yippee-like 5 isoform X1

    UniProtKB/TrEMBL
    A6HA10, D4A4Q3

RNA

  1. XR_005505462.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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