Slc4a1ap solute carrier family 4 member 1 adaptor protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc4a1approvided by RGD
Official Full Name: solute carrier family 4 member 1 adaptor proteinprovided by RGD
Primary source: RGD:1307080
See related: Ensembl:ENSRNOG00000004901 AllianceGenome:RGD:1307080
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable mRNA binding activity. Predicted to be located in nucleoplasm and plasma membrane. Orthologous to human SLC4A1AP (solute carrier family 4 member 1 adaptor protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Muscle (RPKM 242.2), Heart (RPKM 181.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 6q14

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (30625931..30653859, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (24905941..24933651, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (26214083..26241337, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH135398 (e-PCR)
- UniSTS:218675

RH130046 (e-PCR)
- UniSTS:213334

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: kanadaptin

Names: solute carrier family 4 (anion exchanger), member 1, adaptor protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106709.2 → NP_001100179.2 kanadaptin

Status: VALIDATED

Source sequence(s)

JAXUCZ010000006

UniProtKB/TrEMBL

D3ZTF1

Related

ENSRNOP00000006525.8, ENSRNOT00000006525.8

Conserved Domains (3) summary

COG1716
Location:84 → 245

FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]

cd00060
Location:113 → 221

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

pfam00035
Location:316 → 384

dsrm; Double-stranded RNA binding motif

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086024.1 Reference GRCr8

Range

30625931..30653859 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039111909.2 → XP_038967837.1 kanadaptin isoform X1

UniProtKB/TrEMBL

A0A8I6A1K0

Related

ENSRNOP00000085405.1

Conserved Domains (3) summary

PRK00030
Location:12 → 121

minC; septum site-determining protein MinC

cd00060
Location:113 → 221

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd19856
Location:309 → 391

DSRM_Kanadaptin; double-stranded RNA binding motif of Kanadaptin and similar proteins
XM_039111910.2 → XP_038967838.1 kanadaptin isoform X2

Conserved Domains (3) summary

PRK00030
Location:12 → 121

minC; septum site-determining protein MinC

cd00060
Location:113 → 221

FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

cd19856
Location:309 → 391

DSRM_Kanadaptin; double-stranded RNA binding motif of Kanadaptin and similar proteins