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Yeats4 YEATS domain containing 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299810, updated on 11-Apr-2024

Summary

Official Symbol
Yeats4provided by RGD
Official Full Name
YEATS domain containing 4provided by RGD
Primary source
RGD:1305741
See related
Ensembl:ENSRNOG00000005689 AllianceGenome:RGD:1305741
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305741
Summary
Predicted to enable lysine-acetylated histone binding activity and protein C-terminus binding activity. Predicted to be involved in histone H2A acetylation and histone H4 acetylation. Located in nucleus. Biomarker of high grade glioma. Orthologous to human YEATS4 (YEATS domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 405.0), Muscle (RPKM 282.1) and 9 other tissues See more
Orthologs
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Genomic context

See Yeats4 in Genome Data Viewer
Location:
7q22
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (54744220..54751361, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (52858313..52865454, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (60287477..60294618, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093600 Neighboring gene mitochondrial ribosomal protein L47, pseudogene 1 Neighboring gene similar to RIKEN cDNA 9530003J23 Neighboring gene lysozyme C type 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables lysine-acetylated histone binding ISO
Inferred from Sequence Orthology
more info
 
enables modification-dependent protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of double-strand break repair via homologous recombination ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of NuA4 histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of NuA4 histone acetyltransferase complex ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of nucleosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
YEATS domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127527.2NP_001120999.1  YEATS domain-containing protein 4

    See identical proteins and their annotated locations for NP_001120999.1

    Status: PROVISIONAL

    Source sequence(s)
    BC166753
    UniProtKB/TrEMBL
    A6IGR9, B2RYE9, F7FN51
    Related
    ENSRNOP00000007580.4, ENSRNOT00000007580.7
    Conserved Domains (1) summary
    cd16909
    Location:19155
    YEATS_GAS41_like; YEATS domain found in YEATS domain-containing protein 4 and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    54744220..54751361 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)