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Atp23 ATP23 metallopeptidase and ATP synthase assembly factor homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 299828, updated on 5-Mar-2024

Summary

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Official Symbol
Atp23provided by RGD
Official Full Name
ATP23 metallopeptidase and ATP synthase assembly factor homologprovided by RGD
Primary source
RGD:1588587
See related
Ensembl:ENSRNOG00000045629 AllianceGenome:RGD:1588587
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Xrcc6bp1
Summary
Predicted to enable metal ion binding activity and metalloendopeptidase activity. Predicted to be involved in mitochondrial protein processing and mitochondrial proton-transporting ATP synthase complex assembly. Predicted to be located in several cellular components, including cell junction; cytosol; and plasma membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Orthologous to human ATP23 (ATP23 metallopeptidase and ATP synthase assembly factor homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 92.8), Spleen (RPKM 39.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Atp23 in Genome Data Viewer
Location:
7q22
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (64600100..64615240, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (62714752..62729893, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (70183625..70198655, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102557532 Neighboring gene Parkinsonism associated deglycase, pseudogene 1 Neighboring gene uncharacterized LOC120093628 Neighboring gene uncharacterized LOC108351472

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial protein processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial proton-transporting ATP synthase complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
  
located_in cell junction ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
mitochondrial inner membrane protease ATP23 homolog
Names
XRCC6 binding protein 1
NP_001127938.1
XP_038934672.1
XP_038934674.1
XP_038934675.1
XP_038934676.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134466.1 → NP_001127938.1  mitochondrial inner membrane protease ATP23 homolog

    See identical proteins and their annotated locations for NP_001127938.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473950
    UniProtKB/TrEMBL
    A6HQQ8
    Conserved Domains (1) summary
    pfam09768
    Location:52 → 220
    Peptidase_M76; Peptidase M76 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    64600100..64615240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039078744.2 → XP_038934672.1  mitochondrial inner membrane protease ATP23 homolog isoform X1

    UniProtKB/TrEMBL
    M0R4I7
    Related
    ENSRNOP00000064274.2
    Conserved Domains (1) summary
    pfam09768
    Location:52 → 234
    Peptidase_M76; Peptidase M76 family

  2. XM_039078747.2 → XP_038934675.1  mitochondrial inner membrane protease ATP23 homolog isoform X3

    Conserved Domains (1) summary
    pfam09768
    Location:1 → 148
    Peptidase_M76; Peptidase M76 family

  3. XM_039078748.2 → XP_038934676.1  mitochondrial inner membrane protease ATP23 homolog isoform X3

    Conserved Domains (1) summary
    pfam09768
    Location:1 → 148
    Peptidase_M76; Peptidase M76 family

  4. XM_039078746.2 → XP_038934674.1  mitochondrial inner membrane protease ATP23 homolog isoform X2

    Conserved Domains (1) summary
    pfam09768
    Location:52 → 165
    Peptidase_M76; Peptidase M76 family
Nucleotide Protein Strain
Heading Accession and Version

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