Samm50 SAMM50 sorting and assembly machinery component [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Samm50provided by RGD
Official Full Name: SAMM50 sorting and assembly machinery componentprovided by RGD
Primary source: RGD:1303219
See related: Ensembl:ENSRNOG00000011952 AllianceGenome:RGD:1303219
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in cristae formation; mitochondrial respiratory chain complex assembly; and protein insertion into mitochondrial outer membrane. Predicted to be located in mitochondrial outer membrane. Predicted to be part of SAM complex. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease. Orthologous to human SAMM50 (SAMM50 sorting and assembly machinery component). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 457.1), Muscle (RPKM 370.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q34

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (117197460..117221668)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (115317472..115341682)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (125058966..125082506)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in cristae formation	ISO Inferred from Sequence Orthology more info
involved_in cristae formation	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial respiratory chain complex assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial respiratory chain complex assembly	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial respiratory chain complex assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein insertion into mitochondrial outer membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein insertion into mitochondrial outer membrane	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of SAM complex	ISO Inferred from Sequence Orthology more info
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial outer membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: sorting and assembly machinery component 50 homolog

Names: sorting and assembly machinery component 50 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004241.1 → NP_001004241.1 sorting and assembly machinery component 50 homolog

See identical proteins and their annotated locations for NP_001004241.1

Status: PROVISIONAL

Source sequence(s)

BC079302

UniProtKB/Swiss-Prot

Q6AXV4

UniProtKB/TrEMBL

A0A8I6A9E2, A6HTB5

Related

ENSRNOP00000016520.5, ENSRNOT00000016520.7

Conserved Domains (2) summary

pfam01103
Location:151 → 468

Bac_surface_Ag; Surface antigen

pfam07244
Location:45 → 124

POTRA; Surface antigen variable number repeat