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Zfp641 zinc finger protein 641 [ Rattus norvegicus (Norway rat) ]

Gene ID: 300197, updated on 13-Apr-2024

Summary

Official Symbol
Zfp641provided by RGD
Official Full Name
zinc finger protein 641provided by RGD
Primary source
RGD:1310412
See related
Ensembl:ENSRNOG00000032447 AllianceGenome:RGD:1310412
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znf641; RGD1310412
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Orthologous to human ZNF641 (zinc finger protein 641). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 59.1), Adrenal (RPKM 44.1) and 9 other tissues See more
Orthologs
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Genomic context

See Zfp641 in Genome Data Viewer
Location:
7q36
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (131313620..131324149, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (129434576..129444847, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (139897574..139907624, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1, pseudogene 4 Neighboring gene H1.7 linker histone Neighboring gene olfactory receptor family 8 subfamily S member 16 Neighboring gene olfactory receptor family 8 subfamily S member 5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106792.2NP_001100262.1  zinc finger protein 641

    See identical proteins and their annotated locations for NP_001100262.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    A6KC69, D4A704
    Related
    ENSRNOP00000047139.3, ENSRNOT00000045473.6
    Conserved Domains (4) summary
    PLN03206
    Location:1390
    PLN03206; phosphoribosylformylglycinamidine synthase; Provisional
    smart00349
    Location:95156
    KRAB; krueppel associated box
    COG5048
    Location:208402
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:252272
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    131313620..131324149 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039078916.2XP_038934844.1  zinc finger protein 641 isoform X2

    Conserved Domains (4) summary
    PLN03206
    Location:13118
    PLN03206; phosphoribosylformylglycinamidine synthase; Provisional
    smart00349
    Location:91142
    KRAB; krueppel associated box
    COG5048
    Location:194388
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:238258
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_039078915.2XP_038934843.1  zinc finger protein 641 isoform X1

    UniProtKB/TrEMBL
    A6KC69, D4A704
    Conserved Domains (4) summary
    PLN03206
    Location:1390
    PLN03206; phosphoribosylformylglycinamidine synthase; Provisional
    smart00349
    Location:95156
    KRAB; krueppel associated box
    COG5048
    Location:208402
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:252272
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_039078914.2XP_038934842.1  zinc finger protein 641 isoform X1

    UniProtKB/TrEMBL
    A6KC69, D4A704
    Conserved Domains (4) summary
    PLN03206
    Location:1390
    PLN03206; phosphoribosylformylglycinamidine synthase; Provisional
    smart00349
    Location:95156
    KRAB; krueppel associated box
    COG5048
    Location:208402
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:252272
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_039078917.2XP_038934845.1  zinc finger protein 641 isoform X3

    Conserved Domains (3) summary
    smart00349
    Location:3495
    KRAB; krueppel associated box
    COG5048
    Location:147341
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:191211
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_039078918.2XP_038934846.1  zinc finger protein 641 isoform X4

    Conserved Domains (3) summary
    smart00349
    Location:2981
    KRAB; krueppel associated box
    COG5048
    Location:133327
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:177197
    ZF_C2H2; C2H2 Zn finger [structural motif]