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Vwa5a von Willebrand factor A domain containing 5A [ Rattus norvegicus (Norway rat) ]

Gene ID: 301097, updated on 6-Jun-2024

Summary

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Symbol
Vwa5aprovided by RGD
Full Name
von Willebrand factor A domain containing 5Aprovided by RGD
Primary source
RGD:735145
See related
Ensembl:ENSRNOG00000000195 AllianceGenome:RGD:735145
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
masa-1; Loh11cr2a
Summary
Predicted to be located in nucleoplasm. Orthologous to human VWA5A (von Willebrand factor A domain containing 5A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 343.3), Lung (RPKM 181.5) and 9 other tissues See more
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Genomic context

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See Vwa5a in Genome Data Viewer
Location:
8q22
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (47712352..47745847)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (38815176..38848674)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (42442932..42476417)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 8 subfamily B member 59 Neighboring gene olfactory receptor family 8 subfamily G member 51 Neighboring gene olfactory receptor family 8 subfamily B member 53C, pseudogene 1 Neighboring gene olfactory receptor family 8 subfamily B member 53

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Molecular cloning and characterization of LOH11CR2A, a new gene within a refined minimal region of LOH at 11q23. Monaco C, et al. Genomics, 1997 Dec 1. PMID 9417908

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
von Willebrand factor A domain-containing protein 5A
Names
loss of heterozygosity 11 chromosomal region 2 gene A protein homolog
loss of heterozygosity, 11, chromosomal region 2, gene A homolog
mast cell surface antigen 1
von Willebrand factor A domain-containing protein 5A-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001393948.1 → NP_001380877.1  von Willebrand factor A domain-containing protein 5A

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A0A140TAB5
    Related
    ENSRNOP00000015986.8, ENSRNOT00000015986.8
    Conserved Domains (2) summary
    cd01461
    Location:278 → 456
    vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
    cl02699
    Location:1 → 131
    VIT; Vault protein inter-alpha-trypsin domain

RNA

  1. NR_172059.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    47712352..47745847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063265315.1 → XP_063121385.1  von Willebrand factor A domain-containing protein 5A isoform X1

    UniProtKB/TrEMBL
    A0A140TAB5

  2. XM_039081323.2 → XP_038937251.1  von Willebrand factor A domain-containing protein 5A isoform X3

    UniProtKB/TrEMBL
    A0A0H2UH90, A0A140TAB5
    Related
    ENSRNOP00000000211.6
    Conserved Domains (2) summary
    cd01461
    Location:278 → 456
    vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
    cl02699
    Location:1 → 131
    VIT; Vault protein inter-alpha-trypsin domain

  3. XM_063265317.1 → XP_063121387.1  von Willebrand factor A domain-containing protein 5A isoform X2

    UniProtKB/Swiss-Prot
    Q75WE7
    UniProtKB/TrEMBL
    A0A140TAB5

  4. XM_063265319.1 → XP_063121389.1  von Willebrand factor A domain-containing protein 5A isoform X4

    UniProtKB/TrEMBL
    A0A140TAB5

  5. XM_063265316.1 → XP_063121386.1  von Willebrand factor A domain-containing protein 5A isoform X1

    UniProtKB/TrEMBL
    A0A140TAB5

  6. XM_063265318.1 → XP_063121388.1  von Willebrand factor A domain-containing protein 5A isoform X3

    UniProtKB/TrEMBL
    A0A0H2UH90, A0A140TAB5
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q75WE7.1 GenPept UniProtKB/Swiss-Prot:Q75WE7

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