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Tnfaip8l1 TNF alpha induced protein 8 like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 301131, updated on 3-Apr-2024

Summary

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Symbol
Tnfaip8l1provided by RGD
Full Name
TNF alpha induced protein 8 like 1provided by RGD
Primary source
RGD:1588574
See related
Ensembl:ENSRNOG00000069635 AllianceGenome:RGD:1588574
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in negative regulation of TOR signaling. Predicted to be active in cytoplasm. Orthologous to human TNFAIP8L1 (TNF alpha induced protein 8 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 92.8), Spleen (RPKM 69.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tnfaip8l1 in Genome Data Viewer
Location:
9q11
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (1075724..1088256)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (988587..999342)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (10894949..10905647, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene leucine-rich alpha-2-glycoprotein 1 Neighboring gene semaphorin 6B Neighboring gene uncharacterized LOC134480469 Neighboring gene myeloid-derived growth factor Neighboring gene dipeptidyl peptidase 9 Neighboring gene uncharacterized LOC103693194

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The expression of TIPE1 in murine tissues and human cell lines. Cui J, et al. Mol Immunol, 2011 Jul. PMID 21600655
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in negative regulation of TOR signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of TOR signaling ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
tumor necrosis factor alpha-induced protein 8-like protein 1
Names
tumor necrosis factor, alpha-induced protein 8-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399305.1 → NP_001386234.1  tumor necrosis factor alpha-induced protein 8-like protein 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I5ZY03
    Related
    ENSRNOP00000096639.1, ENSRNOT00000097774.1
    Conserved Domains (1) summary
    pfam05527
    Location:25 → 177
    DUF758; Domain of unknown function (DUF758)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    1075724..1088256
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063266830.1 → XP_063122900.1  tumor necrosis factor alpha-induced protein 8-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZY03

  2. XM_006244370.5 → XP_006244432.1  tumor necrosis factor alpha-induced protein 8-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006244432.1

    UniProtKB/TrEMBL
    A0A8I5ZY03
    Related
    ENSRNOP00000084479.1
    Conserved Domains (1) summary
    pfam05527
    Location:25 → 177
    DUF758; Domain of unknown function (DUF758)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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