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Tm4sf5 transmembrane 4 L six family member 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303256, updated on 11-Apr-2024

Summary

Official Symbol
Tm4sf5provided by RGD
Official Full Name
transmembrane 4 L six family member 5provided by RGD
Primary source
RGD:1308709
See related
Ensembl:ENSRNOG00000019510 AllianceGenome:RGD:1308709
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable arginine binding activity. Predicted to be involved in regulation of G1/S transition of mitotic cell cycle. Predicted to be located in lysosomal membrane and plasma membrane. Predicted to be integral component of membrane. Orthologous to human TM4SF5 (transmembrane 4 L six family member 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 1.4), Testes (RPKM 0.2) and 1 other tissue See more
Orthologs
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Genomic context

See Tm4sf5 in Genome Data Viewer
Location:
10q24
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55718014..55724372)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (55219384..55225742)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (57111907..57118299)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 11 Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene zinc finger, MYND-type containing 15 Neighboring gene vitelline membrane outer layer 1 homolog Neighboring gene glycolipid transfer protein domain containing 2 Neighboring gene proteasome 20S subunit beta 6

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables arginine binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in regulation of G1/S transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
transmembrane 4 L6 family member 5
Names
transmembrane 4 superfamily member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107015.1NP_001100485.1  transmembrane 4 L6 family member 5

    See identical proteins and their annotated locations for NP_001100485.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    A6HG57, D4ABR9
    Related
    ENSRNOP00000026437.4, ENSRNOT00000026437.5
    Conserved Domains (1) summary
    pfam05805
    Location:1189
    L6_membrane; L6 membrane protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    55718014..55724372
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)