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Slc7a4 solute carrier family 7, member 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303787, updated on 5-Mar-2024

Summary

Official Symbol
Slc7a4provided by RGD
Official Full Name
solute carrier family 7, member 4provided by RGD
Primary source
RGD:1305905
See related
Ensembl:ENSRNOG00000001874 AllianceGenome:RGD:1305905
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transport. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human SLC7A4 (solute carrier family 7 member 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 49.7), Adrenal (RPKM 20.6) and 8 other tissues See more
Orthologs
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Genomic context

Location:
11q23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (96939456..96943127)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (83435093..83439078)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (87445585..87450008, complement)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene sphingomyelin phosphodiesterase 4 Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 2, pseudogene 2 Neighboring gene uncharacterized LOC108352364 Neighboring gene purinergic receptor P2X 6 Neighboring gene leucine rich repeat containing 74B Neighboring gene translation machinery-associated protein 16 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in amino acid transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
cationic amino acid transporter 4
Names
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
solute carrier family 7 (orphan transporter), member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107078.2NP_001100548.1  cationic amino acid transporter 4

    See identical proteins and their annotated locations for NP_001100548.1

    Status: PROVISIONAL

    Source sequence(s)
    BC169079
    UniProtKB/TrEMBL
    B5DFJ0, F7FP86
    Conserved Domains (1) summary
    TIGR00906
    Location:14592
    2A0303; cationic amino acid transport permease

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    96939456..96943127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)