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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001270598.1 → NP_001257527.1 insulin-like growth factor 2 mRNA-binding protein 2 isoform 1
See identical proteins and their annotated locations for NP_001257527.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) uses an upstream start codon, and encodes the full-length isoform (1).
- Source sequence(s)
-
JAXUCZ010000011
- UniProtKB/TrEMBL
- A6JS60, D3ZWZ6
- Related
- ENSRNOP00000037578.6, ENSRNOT00000036958.7
- Conserved Domains (5) summary
-
- COG0724
Location:3 → 78
- RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
- cd00105
Location:270 → 335
- KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
- cd02396
Location:422 → 486
- PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
- cd12626
Location:2 → 78
- RRM1_IGF2BP2; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
- cd12629
Location:82 → 157
- RRM2_IGF2BP2; RNA recognition motif 2 in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
-
NM_001270599.1 → NP_001257528.1 insulin-like growth factor 2 mRNA-binding protein 2 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) uses an in-frame downstream start codon, and encodes a shorter isoform (2) missing N-terminal 68 aa compared to isoform 1. It lacks a conserved N-terminal RNA Recognition Motif (RRM) and is predicted to differ functionally from the full-length isoform (PMID:22427968).
- Source sequence(s)
-
JAXUCZ010000011
- Conserved Domains (3) summary
-
- cd00105
Location:202 → 267
- KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
- cd02396
Location:354 → 418
- PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
- cl17169
Location:14 → 89
- RRM_SF; RNA recognition motif (RRM) superfamily
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCr8
Genomic
-
NC_086029.1 Reference GRCr8
- Range
-
92378908..92478893
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)