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Wdr5b WD repeat domain 5B [ Rattus norvegicus (Norway rat) ]

Gene ID: 303907, updated on 5-Mar-2024

Summary

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Official Symbol
Wdr5bprovided by RGD
Official Full Name
WD repeat domain 5Bprovided by RGD
Primary source
RGD:1308567
See related
Ensembl:ENSRNOG00000002253 AllianceGenome:RGD:1308567
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable histone binding activity. Predicted to be involved in histone H3-K4 methylation. Predicted to be part of Set1C/COMPASS complex. Orthologous to human WDR5B (WD repeat domain 5B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See Wdr5b in Genome Data Viewer
Location:
11q22
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (78216266..78218125, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (64710945..64712804, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (67645959..67647818, complement)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481076 Neighboring gene RAN binding protein 1 like 1 Neighboring gene mitochondrial matrix import factor 23 Neighboring gene family with sequence similarity 162, member A Neighboring gene karyopherin subunit alpha 1 Neighboring gene uncharacterized LOC134481077 Neighboring gene poly (ADP-ribose) polymerase family, member 9 Neighboring gene deltex E3 ubiquitin ligase 3L

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. Brown SA, et al. Science, 2005 Apr 29. PMID 15860628
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
part_of Set1C/COMPASS complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
WD repeat-containing protein 5B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024766.1 → NP_001019937.1  WD repeat-containing protein 5B

    See identical proteins and their annotated locations for NP_001019937.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097449
    UniProtKB/Swiss-Prot
    Q4V8C4
    UniProtKB/TrEMBL
    A6IRE4
    Related
    ENSRNOP00000003068.2, ENSRNOT00000003068.4
    Conserved Domains (2) summary
    cd00200
    Location:31 → 325
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:42 → 79
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    78216266..78218125 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4V8C4.1 GenPept UniProtKB/Swiss-Prot:Q4V8C4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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