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Cox19 cytochrome c oxidase assembly factor COX19 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304330, updated on 30-Mar-2024

Summary

Official Symbol
Cox19provided by RGD
Official Full Name
cytochrome c oxidase assembly factor COX19provided by RGD
Primary source
RGD:1305631
See related
AllianceGenome:RGD:1305631
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305631
Summary
Predicted to be involved in cellular copper ion homeostasis and mitochondrial cytochrome c oxidase assembly. Predicted to be located in cytosol and mitochondrion. Predicted to be active in mitochondrial intermembrane space. Orthologous to human COX19 (cytochrome c oxidase assembly factor COX19). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 88.6), Heart (RPKM 64.1) and 9 other tissues See more
Orthologs
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Genomic context

Location:
12q11
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (20417389..20426868)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (15303535..15313014)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (17395624..17405103)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 7 open reading frame 50 Neighboring gene microRNA 339 Neighboring gene cytochrome P450, family 2, subfamily w, polypeptide 1 Neighboring gene ArfGAP with dual PH domains 1 Neighboring gene guided entry of tail-anchored proteins factor 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in intracellular copper ion homeostasis ISO
Inferred from Sequence Orthology
more info
 
involved_in mitochondrial cytochrome c oxidase assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in mitochondrial intermembrane space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial intermembrane space ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
COX19 cytochrome c oxidase assembly homolog
Names
COX19 cytochrome c oxidase assembly factor
cytochrome c oxidase assembly homolog 19
cytochrome c oxidase assembly protein 19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107126.2NP_001100596.1  COX19 cytochrome c oxidase assembly homolog

    See identical proteins and their annotated locations for NP_001100596.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    A6K1W3
    Conserved Domains (1) summary
    pfam06747
    Location:3064
    CHCH; CHCH domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    20417389..20426868
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)