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Klhdc8a kelch domain containing 8A [ Rattus norvegicus (Norway rat) ]

Gene ID: 305096, updated on 24-Apr-2024

Summary

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Official Symbol
Klhdc8aprovided by RGD
Official Full Name
kelch domain containing 8Aprovided by RGD
Primary source
RGD:1305132
See related
Ensembl:ENSRNOG00000000036 AllianceGenome:RGD:1305132
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305132
Summary
Orthologous to human KLHDC8A (kelch domain containing 8A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 289.5), Testes (RPKM 60.1) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Klhdc8a in Genome Data Viewer
Location:
13q13
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (46287011..46296429)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (43735702..43744277)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (49074644..49082729)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481495 Neighboring gene cyclin-dependent kinase 18 Neighboring gene BLACAT1 overlapping LEMD1 locus Neighboring gene LEM domain containing 1 Neighboring gene microRNA 135b Neighboring gene uncharacterized LOC120096185 Neighboring gene NUAK family kinase 2 Neighboring gene transmembrane and coiled-coil domain family 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
kelch domain-containing protein 8A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100683.1 → NP_001094153.1  kelch domain-containing protein 8A isoform 1

    See identical proteins and their annotated locations for NP_001094153.1

    Status: VALIDATED

    Source sequence(s)
    BC089928, CK471950, JAXUCZ010000013
    UniProtKB/TrEMBL
    A6IC47, F2Z3R0
    Related
    ENSRNOP00000000041.4, ENSRNOT00000000041.7
    Conserved Domains (2) summary
    PHA03098
    Location:5 → 209
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:21 → 65
    Kelch; KELCH repeat [structural motif]

  2. NM_001429588.1 → NP_001416517.1  kelch domain-containing protein 8A isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013

  3. NM_001429589.1 → NP_001416518.1  kelch domain-containing protein 8A isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    46287011..46296429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039090836.2 → XP_038946764.1  kelch domain-containing protein 8A isoform X4

    Conserved Domains (2) summary
    PHA03098
    Location:5 → 184
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:21 → 65
    Kelch; KELCH repeat [structural motif]

  2. XM_039090833.2 → XP_038946761.1  kelch domain-containing protein 8A isoform X1

    UniProtKB/TrEMBL
    A6IC47, F2Z3R0
    Conserved Domains (2) summary
    PHA03098
    Location:5 → 209
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:21 → 65
    Kelch; KELCH repeat [structural motif]

  3. XM_039090834.2 → XP_038946762.1  kelch domain-containing protein 8A isoform X2

    Conserved Domains (2) summary
    PHA03098
    Location:48 → 252
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:84 → 127
    Kelch; KELCH repeat [structural motif]

  4. XM_039090835.2 → XP_038946763.1  kelch domain-containing protein 8A isoform X3

    Conserved Domains (2) summary
    PHA03098
    Location:1 → 199
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:31 → 74
    Kelch; KELCH repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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