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Tapt1 transmembrane anterior posterior transformation 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 305386, updated on 11-Apr-2024

Summary

Official Symbol
Tapt1provided by RGD
Official Full Name
transmembrane anterior posterior transformation 1provided by RGD
Primary source
RGD:1309656
See related
Ensembl:ENSRNOG00000003174 AllianceGenome:RGD:1309656
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309656
Summary
Predicted to be involved in maintenance of protein localization in endoplasmic reticulum and positive regulation of cilium assembly. Predicted to act upstream of or within embryonic skeletal system development. Predicted to be located in centrosome. Predicted to be active in ciliary basal body. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human TAPT1 (transmembrane anterior posterior transformation 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 336.1), Muscle (RPKM 264.1) and 9 other tissues See more
Orthologs
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Genomic context

Location:
14q21
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (71085966..71132228)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (66873467..66919737)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (71416153..71462646)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene Rac family small GTPase 1 like Neighboring gene uncharacterized LOC120096622 Neighboring gene uncharacterized LOC120096623 Neighboring gene U7 small nuclear RNA Neighboring gene prominin 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cartilage development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within embryonic skeletal system development ISO
Inferred from Sequence Orthology
more info
 
involved_in ossification IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of cilium assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
transmembrane anterior posterior transformation protein 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    71085966..71132228
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039092783.2XP_038948711.1  transmembrane anterior posterior transformation protein 1 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8I6A632, D4A533
    Related
    ENSRNOP00000087570.1
    Conserved Domains (1) summary
    pfam05346
    Location:152456
    DUF747; Eukaryotic membrane protein family
  2. XM_039092784.2XP_038948712.1  transmembrane anterior posterior transformation protein 1 homolog isoform X2

    Conserved Domains (1) summary
    pfam05346
    Location:16320
    DUF747; Eukaryotic membrane protein family