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Stk32b serine/threonine kinase 32B [ Rattus norvegicus (Norway rat) ]

Gene ID: 305431, updated on 13-Apr-2024

Summary

Official Symbol
Stk32bprovided by RGD
Official Full Name
serine/threonine kinase 32Bprovided by RGD
Primary source
RGD:1306173
See related
Ensembl:ENSRNOG00000031397 AllianceGenome:RGD:1306173
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Orthologous to human STK32B (serine/threonine kinase 32B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 25.6), Testes (RPKM 4.0) and 3 other tissues See more
Orthologs
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Genomic context

Location:
14q21
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (77300675..77562721)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (73077944..73337976)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (77837073..78098731)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096636 Neighboring gene cytokine like 1 Neighboring gene uncharacterized LOC134481774 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC120096637 Neighboring gene prostaglandin E synthase 3, pseudogene 1 Neighboring gene EvC ciliary complex subunit 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
serine/threonine-protein kinase 32B
NP_001100694.1
XP_017454686.1
XP_038947875.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107224.3NP_001100694.1  serine/threonine-protein kinase 32B

    See identical proteins and their annotated locations for NP_001100694.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/TrEMBL
    A0A0G2JWX7, A6IJV9, F1M3G9
    Related
    ENSRNOP00000070055.2, ENSRNOT00000081198.2
    Conserved Domains (2) summary
    smart00220
    Location:23272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05578
    Location:22283
    STKc_Yank1; Catalytic domain of the Serine/Threonine Kinase, Yank1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    77300675..77562721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039091947.2XP_038947875.1  serine/threonine-protein kinase 32B isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:22187
    PKc_like; Protein Kinases, catalytic domain
  2. XM_017599197.3XP_017454686.1  serine/threonine-protein kinase 32B isoform X1

    UniProtKB/TrEMBL
    A0A0G2JWX7