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Slc39a2 solute carrier family 39 member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 305846, updated on 5-Mar-2024

Summary

Official Symbol
Slc39a2provided by RGD
Official Full Name
solute carrier family 39 member 2provided by RGD
Primary source
RGD:1306291
See related
Ensembl:ENSRNOG00000010375 AllianceGenome:RGD:1306291
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to act upstream of or within zinc ion transport. Predicted to be located in cytoplasmic ribonucleoprotein granule and cytoplasmic vesicle. Predicted to be active in plasma membrane. Orthologous to human SLC39A2 (solute carrier family 39 member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Lung (RPKM 49.1), Heart (RPKM 31.5) and 1 other tissue See more
Orthologs
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Genomic context

Location:
15p14
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (27063699..27066349)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (24590738..24592850)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (28295044..28297688)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene eosinophil-associated, ribonuclease A family, member 1 Neighboring gene methyltransferase like 17 Neighboring gene NDRG family member 2 Neighboring gene tubulin polymerization-promoting protein family member 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables zinc ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cadmium ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in keratinocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in zinc ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in zinc ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within zinc ion transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasmic ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc transporter ZIP2
Names
solute carrier family 39 (zinc transporter), member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107260.1NP_001100730.1  zinc transporter ZIP2

    See identical proteins and their annotated locations for NP_001100730.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474040
    UniProtKB/TrEMBL
    A6KEE1, A6KEE2, D3ZIN1
    Related
    ENSRNOP00000013786.5, ENSRNOT00000013786.7
    Conserved Domains (1) summary
    pfam02535
    Location:6306
    Zip; ZIP Zinc transporter

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    27063699..27066349
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063274222.1XP_063130292.1  zinc transporter ZIP2 isoform X1