Lonrf1 LON peptidase N-terminal domain and ring finger 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lonrf1provided by RGD
Official Full Name: LON peptidase N-terminal domain and ring finger 1provided by RGD
Primary source: RGD:1562583
See related: Ensembl:ENSRNOG00000053706 AllianceGenome:RGD:1562583
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1562583
Summary: Predicted to enable metal ion binding activity. Orthologous to human LONRF1 (LON peptidase N-terminal domain and ring finger 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Lung (RPKM 37.8), Muscle (RPKM 35.3) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	16	NC_086034.1 (62687931..62718525)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	16	NC_051351.1 (55984572..56015156)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	16	NC_005115.4 (59564548..59594252)

Chromosome 16 - NC_086034.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain

XM_063275867.1 → XP_063131937.1 LON peptidase N-terminal domain and RING finger protein 1 isoform X1
XM_017600372.3 → XP_017455861.2 LON peptidase N-terminal domain and RING finger protein 1 isoform X2

UniProtKB/TrEMBL

A0A0G2K313

Related

ENSRNOP00000072463.2

Conserved Domains (7) summary

COG0457
Location:209 → 336

TPR; Tetratricopeptide (TPR) repeat [General function prediction only]

COG5574
Location:455 → 551

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

sd00006
Location:237 → 264

TPR; TPR repeat [structural motif]

cd00162
Location:154 → 189

RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]

cd16514
Location:500 → 541

RING2-HC_LONFs; RING finger 2, HC subclass, found in the LON peptidase N-terminal domain and RING finger proteins family

pfam02190
Location:591 → 789

LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain

cl17238
Location:154 → 190

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain