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Slc35b3 solute carrier family 35 member B3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 306866, updated on 13-Apr-2024

Summary

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Official Symbol
Slc35b3provided by RGD
Official Full Name
solute carrier family 35 member B3provided by RGD
Primary source
RGD:1307183
See related
Ensembl:ENSRNOG00000016174 AllianceGenome:RGD:1307183
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity. Predicted to be involved in 3'-phospho-5'-adenylyl sulfate transmembrane transport. Predicted to be integral component of Golgi membrane and integral component of endoplasmic reticulum membrane. Orthologous to human SLC35B3 (solute carrier family 35 member B3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 106.4), Spleen (RPKM 100.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Slc35b3 in Genome Data Viewer
Location:
17p12
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (26052249..26078686)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (25846590..25873115)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (26478777..26505225)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene N-terminal Xaa-Pro-Lys N-methyltransferase 1, pseudogene 1 Neighboring gene uncharacterized LOC120097954 Neighboring gene protein regulator of cytokinesis 1, pseudogene 1 Neighboring gene DNA polymerase epsilon 3, accessory subunit, pseudogene 2 Neighboring gene eukaryotic translation elongation factor 1 epsilon 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in 3'-phospho-5'-adenylyl sulfate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in 3'-phosphoadenosine 5'-phosphosulfate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
adenosine 3'-phospho 5'-phosphosulfate transporter 2
Names
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107346.1 → NP_001100816.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A0A8I6ACP7, A6J795
    Related
    ENSRNOP00000089959.1, ENSRNOT00000112405.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    26052249..26078686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006253853.5 → XP_006253915.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X4

    See identical proteins and their annotated locations for XP_006253915.1

    Conserved Domains (1) summary
    pfam08449
    Location:90 → 341
    UAA; UAA transporter family

  2. XM_006253854.5 → XP_006253916.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X5

    See identical proteins and their annotated locations for XP_006253916.1

    Conserved Domains (1) summary
    pfam08449
    Location:90 → 340
    UAA; UAA transporter family

  3. XM_039096462.2 → XP_038952390.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X3

    Conserved Domains (1) summary
    pfam08449
    Location:90 → 367
    UAA; UAA transporter family

  4. XM_225253.11 → XP_225253.5  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X1

    See identical proteins and their annotated locations for XP_225253.5

    UniProtKB/TrEMBL
    D4AAG3
    Related
    ENSRNOP00000021670.4
    Conserved Domains (1) summary
    pfam08449
    Location:90 → 381
    UAA; UAA transporter family

  5. XM_039096465.2 → XP_038952393.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X8

    Conserved Domains (1) summary
    pfam08449
    Location:90 → 240
    UAA; UAA transporter family

  6. XM_039096464.2 → XP_038952392.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X8

    Conserved Domains (1) summary
    pfam08449
    Location:90 → 240
    UAA; UAA transporter family

  7. XM_039096466.2 → XP_038952394.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X8

    Conserved Domains (1) summary
    pfam08449
    Location:90 → 240
    UAA; UAA transporter family

  8. XM_006253852.5 → XP_006253914.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X3

    See identical proteins and their annotated locations for XP_006253914.1

    Conserved Domains (1) summary
    pfam08449
    Location:90 → 367
    UAA; UAA transporter family

  9. XM_039096463.2 → XP_038952391.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X7

    Conserved Domains (1) summary
    pfam08449
    Location:90 → 301
    UAA; UAA transporter family

  10. XM_039096467.2 → XP_038952395.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X9

    Conserved Domains (1) summary
    pfam08449
    Location:90 → 240
    UAA; UAA transporter family

  11. XM_039096468.2 → XP_038952396.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X10

    Conserved Domains (1) summary
    pfam08449
    Location:48 → 259
    UAA; UAA transporter family

  12. XM_063276389.1 → XP_063132459.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X12

  13. XM_063276387.1 → XP_063132457.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X6

    UniProtKB/TrEMBL
    A6J797

  14. XM_006253856.4 → XP_006253918.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X2

    See identical proteins and their annotated locations for XP_006253918.1

    UniProtKB/TrEMBL
    A0A8I6ACP7, A6J795
    Conserved Domains (1) summary
    pfam08449
    Location:48 → 339
    UAA; UAA transporter family

  15. XM_063276388.1 → XP_063132458.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X10

  16. XM_006253850.3 → XP_006253912.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X2

    See identical proteins and their annotated locations for XP_006253912.1

    UniProtKB/TrEMBL
    A0A8I6ACP7, A6J795
    Conserved Domains (1) summary
    pfam08449
    Location:48 → 339
    UAA; UAA transporter family

  17. XM_006253855.5 → XP_006253917.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X2

    See identical proteins and their annotated locations for XP_006253917.1

    UniProtKB/TrEMBL
    A0A8I6ACP7, A6J795
    Conserved Domains (1) summary
    pfam08449
    Location:48 → 339
    UAA; UAA transporter family

  18. XM_039096469.1 → XP_038952397.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X11

    Conserved Domains (1) summary
    pfam08449
    Location:1 → 225
    UAA; UAA transporter family

  19. XM_039096470.1 → XP_038952398.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X13

    Conserved Domains (1) summary
    pfam08449
    Location:1 → 166
    UAA; UAA transporter family

  20. XM_039096471.1 → XP_038952399.1  adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X13

    Conserved Domains (1) summary
    pfam08449
    Location:1 → 166
    UAA; UAA transporter family

RNA

  1. XR_010058863.1 RNA Sequence

  2. XR_005495896.2 RNA Sequence

  3. XR_010058864.1 RNA Sequence

  4. XR_005495897.2 RNA Sequence

  5. XR_005495898.2 RNA Sequence

  6. XR_005495901.2 RNA Sequence

  7. XR_010058865.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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