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Snx20 sorting nexin 20 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307742, updated on 5-Mar-2024

Summary

Official Symbol
Snx20provided by RGD
Official Full Name
sorting nexin 20provided by RGD
Primary source
RGD:1307787
See related
Ensembl:ENSRNOG00000014202 AllianceGenome:RGD:1307787
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Slic1; RGD1307787
Summary
Predicted to enable phosphatidylinositol-3-phosphate binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in protein transport. Predicted to be located in nucleoplasm. Predicted to be active in early endosome membrane. Orthologous to human SNX20 (sorting nexin 20). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 111.4), Thymus (RPKM 102.6) and 7 other tissues See more
Orthologs
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Genomic context

Location:
19p11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (34609397..34618569)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (18435935..18445108)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (19395655..19404846)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098599 Neighboring gene nucleotide-binding oligomerization domain containing 2 Neighboring gene uncharacterized LOC134483298 Neighboring gene NKD inhibitor of WNT signaling pathway 1 Neighboring gene uncharacterized LOC134483621

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC108869

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables phosphatidylinositol phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphatidylinositol-3-phosphate binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol-3-phosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables phosphatidylinositol-4,5-bisphosphate binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol-4,5-bisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in early endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in early endosome membrane ISO
Inferred from Sequence Orthology
more info
 
located_in early endosome membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sorting nexin-20
Names
selectin ligand interactor cytoplasmic-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024999.1NP_001020170.1  sorting nexin-20

    See identical proteins and their annotated locations for NP_001020170.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091194
    UniProtKB/Swiss-Prot
    Q5BK61
    Related
    ENSRNOP00000019130.4, ENSRNOT00000019130.6
    Conserved Domains (1) summary
    cl02563
    Location:73186
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    34609397..34618569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)