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Gfod2 Gfo/Idh/MocA-like oxidoreductase domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307801, updated on 3-Apr-2024

Summary

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Official Symbol
Gfod2provided by RGD
Official Full Name
Gfo/Idh/MocA-like oxidoreductase domain containing 2provided by RGD
Primary source
RGD:1311198
See related
Ensembl:ENSRNOG00000017953 AllianceGenome:RGD:1311198
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311198
Summary
Predicted to enable nucleotide binding activity and oxidoreductase activity. Predicted to be involved in extracellular matrix organization. Predicted to be active in extracellular matrix. Orthologous to human GFOD2 (glucose-fructose oxidoreductase domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 60.4), Lung (RPKM 28.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gfod2 in Genome Data Viewer
Location:
19q12
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (50508626..50556945, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (33599689..33647060, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (37678488..37725623, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 16 open reading frame 86 Neighboring gene par-6 family cell polarity regulator alpha Neighboring gene enkurin domain containing 1 Neighboring gene small nuclear ribonucleoprotein polypeptide G, pseudogene 2 Neighboring gene uncharacterized LOC134483349 Neighboring gene RAN binding protein 10 Neighboring gene uncharacterized LOC108348930 Neighboring gene translin-associated factor X interacting protein 1 Neighboring gene centromere protein T

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Transcriptome-based systematic identification of extracellular matrix proteins. Manabe R, et al. Proc Natl Acad Sci U S A, 2008 Sep 2. PMID 18757743, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in extracellular matrix organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within extracellular matrix organization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular matrix ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glucose-fructose oxidoreductase domain-containing protein 2
Names
glucose-fructose oxidoreductase domain containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107421.1 → NP_001100891.1  glucose-fructose oxidoreductase domain-containing protein 2

    See identical proteins and their annotated locations for NP_001100891.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473972
    UniProtKB/TrEMBL
    B1WBV3, F7EU20
    Related
    ENSRNOP00000024197.3, ENSRNOT00000024197.5
    Conserved Domains (1) summary
    COG0673
    Location:7 → 365
    MviM; Predicted dehydrogenase [General function prediction only]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    50508626..50556945 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063278026.1 → XP_063134096.1  glucose-fructose oxidoreductase domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B1WBV3, F7EU20

  2. XM_063278025.1 → XP_063134095.1  glucose-fructose oxidoreductase domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B1WBV3, F7EU20

  3. XM_063278027.1 → XP_063134097.1  glucose-fructose oxidoreductase domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B1WBV3, F7EU20

  4. XM_039097732.2 → XP_038953660.1  glucose-fructose oxidoreductase domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B1WBV3, F7EU20
    Conserved Domains (1) summary
    COG0673
    Location:7 → 365
    MviM; Predicted dehydrogenase [General function prediction only]

  5. XM_063278028.1 → XP_063134098.1  glucose-fructose oxidoreductase domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B1WBV3, F7EU20

  6. XM_063278024.1 → XP_063134094.1  glucose-fructose oxidoreductase domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B1WBV3, F7EU20

  7. XM_063278029.1 → XP_063134099.1  glucose-fructose oxidoreductase domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B1WBV3, F7EU20

  8. XM_039097734.2 → XP_038953662.1  glucose-fructose oxidoreductase domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    B1WBV3, F7EU20
    Conserved Domains (1) summary
    COG0673
    Location:7 → 365
    MviM; Predicted dehydrogenase [General function prediction only]
Nucleotide Protein Strain
Heading Accession and Version

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