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Zfp612 zinc finger protein 612 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307839, updated on 3-Apr-2024

Summary

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Symbol
Zfp612provided by RGD
Full Name
zinc finger protein 612provided by RGD
Primary source
RGD:1307197
See related
Ensembl:ENSRNOG00000016971 AllianceGenome:RGD:1307197
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zfp23; Znf23
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF23 (zinc finger protein 23). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 137.0), Adrenal (RPKM 111.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp612 in Genome Data Viewer
Location:
19q12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (54963400..54976888)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (38053953..38071196)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (41556907..41570352, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483643 Neighboring gene carbohydrate sulfotransferase 4 Neighboring gene uncharacterized LOC120098624 Neighboring gene TLE family member 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 23
Names
zinc finger protein 23 (KOX 16)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107428.2 → NP_001100898.2  zinc finger protein 23

    See identical proteins and their annotated locations for NP_001100898.2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/TrEMBL
    D3ZLR3
    Conserved Domains (3) summary
    smart00349
    Location:14 → 74
    KRAB; krueppel associated box
    COG5048
    Location:254 → 660
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:454 → 474
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    54963400..54976888
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063278056.1 → XP_063134126.1  zinc finger protein 23 isoform X2

    UniProtKB/TrEMBL
    D3ZLR3

  2. XM_039097754.2 → XP_038953682.1  zinc finger protein 23 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:14 → 74
    KRAB; krueppel associated box
    COG5048
    Location:254 → 660
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:454 → 474
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_063278055.1 → XP_063134125.1  zinc finger protein 23 isoform X2

    UniProtKB/TrEMBL
    D3ZLR3

  4. XM_006255588.4 → XP_006255650.1  zinc finger protein 23 isoform X1

    See identical proteins and their annotated locations for XP_006255650.1

    UniProtKB/TrEMBL
    D3ZLR3
    Conserved Domains (3) summary
    smart00349
    Location:14 → 74
    KRAB; krueppel associated box
    COG5048
    Location:254 → 660
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:454 → 474
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_039097756.2 → XP_038953684.1  zinc finger protein 23 isoform X2

    UniProtKB/TrEMBL
    D3ZLR3
    Related
    ENSRNOP00000022757.5
    Conserved Domains (3) summary
    smart00349
    Location:9 → 69
    KRAB; krueppel associated box
    COG5048
    Location:249 → 655
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:449 → 469
    ZF_C2H2; C2H2 Zn finger [structural motif]

  6. XM_006255589.4 → XP_006255651.1  zinc finger protein 23 isoform X1

    See identical proteins and their annotated locations for XP_006255651.1

    UniProtKB/TrEMBL
    D3ZLR3
    Conserved Domains (3) summary
    smart00349
    Location:14 → 74
    KRAB; krueppel associated box
    COG5048
    Location:254 → 660
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:454 → 474
    ZF_C2H2; C2H2 Zn finger [structural motif]

  7. XM_039097757.2 → XP_038953685.1  zinc finger protein 23 isoform X2

    UniProtKB/TrEMBL
    D3ZLR3
    Conserved Domains (3) summary
    smart00349
    Location:9 → 69
    KRAB; krueppel associated box
    COG5048
    Location:249 → 655
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:449 → 469
    ZF_C2H2; C2H2 Zn finger [structural motif]

  8. XM_039097758.2 → XP_038953686.1  zinc finger protein 23 isoform X3

    Conserved Domains (3) summary
    COG5048
    Location:212 → 618
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:412 → 432
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:1 → 32
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

  9. XM_017601293.3 → XP_017456782.1  zinc finger protein 23 isoform X3

    Conserved Domains (3) summary
    COG5048
    Location:212 → 618
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:412 → 432
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:1 → 32
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
Nucleotide Protein Strain
Heading Accession and Version

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