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Rab30 RAB30, member RAS oncogene family [ Rattus norvegicus (Norway rat) ]

Gene ID: 308821, updated on 11-Apr-2024

Summary

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Official Symbol
Rab30provided by RGD
Official Full Name
RAB30, member RAS oncogene familyprovided by RGD
Primary source
RGD:1309507
See related
Ensembl:ENSRNOG00000010224 AllianceGenome:RGD:1309507
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rsb30
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in Golgi organization. Predicted to be located in Golgi cisterna and cis-Golgi network. Predicted to be active in trans-Golgi network. Orthologous to human RAB30 (RAB30, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 81.0), Liver (RPKM 54.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rab30 in Genome Data Viewer
Location:
1q32
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (156216137..156310778)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (146803719..146898369)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (157573344..157667973)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S3a, pseudogene 1 Neighboring gene uncharacterized LOC100912031 Neighboring gene small nucleolar RNA SNORA70 Neighboring gene DNA damage-induced apoptosis suppressor Neighboring gene prolylcarboxypeptidase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Rab30 is required for the morphological integrity of the Golgi apparatus. Kelly EE, et al. Biol Cell, 2012 Feb. PMID 22188167
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC108822

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
  
involved_in Rab protein signal transduction IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi cisterna IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi cisterna ISO
Inferred from Sequence Orthology
more info
  
located_in cis-Golgi network ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ras-related protein Rab-30

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001015012.3 → NP_001015012.1  ras-related protein Rab-30 isoform b

    See identical proteins and their annotated locations for NP_001015012.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I6ANI9, Q5BK72
    Conserved Domains (1) summary
    cl38936
    Location:3 → 143
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. NM_001399386.2 → NP_001386315.1  ras-related protein Rab-30 isoform a

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A0G2JTT4, A6I665
    Conserved Domains (1) summary
    cd04114
    Location:3 → 171
    Rab30; Rab GTPase family 30 (Rab30)

  3. NM_001399387.2 → NP_001386316.1  ras-related protein Rab-30 isoform a

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A0G2JTT4, A6I665
    Conserved Domains (1) summary
    cd04114
    Location:3 → 171
    Rab30; Rab GTPase family 30 (Rab30)

  4. NM_001399388.2 → NP_001386317.1  ras-related protein Rab-30 isoform a

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A0G2JTT4, A6I665
    Related
    ENSRNOP00000068836.1, ENSRNOT00000092066.2
    Conserved Domains (1) summary
    cd04114
    Location:3 → 171
    Rab30; Rab GTPase family 30 (Rab30)

  5. NM_001399389.2 → NP_001386318.1  ras-related protein Rab-30 isoform a

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A0G2JTT4, A6I665
    Conserved Domains (1) summary
    cd04114
    Location:3 → 171
    Rab30; Rab GTPase family 30 (Rab30)

  6. NM_001399390.2 → NP_001386319.1  ras-related protein Rab-30 isoform b

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    Q5BK72
    Related
    ENSRNOP00000013851.3, ENSRNOT00000013851.7
    Conserved Domains (1) summary
    cl38936
    Location:3 → 143
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. NR_174183.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    156216137..156310778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262746.1 → XP_063118816.1  ras-related protein Rab-30 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JTT4, A6I665

  2. XM_063262747.1 → XP_063118817.1  ras-related protein Rab-30 isoform X2

    UniProtKB/TrEMBL
    Q5BK72

  3. XM_017589171.3 → XP_017444660.1  ras-related protein Rab-30 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JTT4, A6I665
    Conserved Domains (1) summary
    cd04114
    Location:3 → 171
    Rab30; Rab GTPase family 30 (Rab30)
Nucleotide Protein Strain
Heading Accession and Version

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